Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46.
about
Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy.Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.Distinct activity of the bone-targeted gallium compound KP46 against osteosarcoma cells - synergism with autophagy inhibition.Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs.Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established.
P2860
Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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2014年學術文章
@zh-hant
name
Calpain-mediated integrin dere ...... icancer gallium compound KP46.
@en
type
label
Calpain-mediated integrin dere ...... icancer gallium compound KP46.
@en
prefLabel
Calpain-mediated integrin dere ...... icancer gallium compound KP46.
@en
P2093
P50
P1476
Calpain-mediated integrin dere ...... icancer gallium compound KP46.
@en
P2093
Johannes Gojo
Karin Nowikovsky
Martin Holcmann
Nastasia Wilfinger
Rosa Lemmens-Gruber
Sushilla Schoonhoven
Theresa Tuder
Thomas Schöfl
P304
P356
10.1158/1535-7163.MCT-14-0087
P577
2014-07-31T00:00:00Z