"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".

about

CD30 Downregulation, MMAE Resistance, and MDR1 Upregulation Are All Associated with Resistance to Brentuximab Vedotin.Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel.

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P2860

"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".

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2014 nî lūn-bûn

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2014年の論文

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"Effect of the drug transporte ...... he taxane analog BMS-275,183".

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Dick Pluim

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Jan H M Schellens

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Jos H Beijnen

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Olaf van Tellingen

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Roberto Mazzanti

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P2860

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Membrane transporters in drug development

Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML).

Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein.

The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins.

Pharmacogenetics of taxanes: impact of gene polymorphisms of drug transporters on pharmacokinetics and toxicity.

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid.

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s10637-014-0143-0

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1083-1095

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10.1007/S10637-014-0143-0

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"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".

about

P2860

P2860

"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".

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