Cyclopropane pipecolic acids as templates for linear and cyclic peptidomimetics: application in the synthesis of an Arg-Gly-Asp (RGD)-containing peptide as an αvβ3 integrin ligand.

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Synthesis and conformational analysis of peptides embodying 2,3-methanopipecolic acids.Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.

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P2860

Cyclopropane pipecolic acids as templates for linear and cyclic peptidomimetics: application in the synthesis of an Arg-Gly-Asp (RGD)-containing peptide as an αvβ3 integrin ligand.

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2014 nî lūn-bûn

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name

Cyclopropane pipecolic acids a ...... de as an αvβ3 integrin ligand.

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type

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Cyclopropane pipecolic acids a ...... de as an αvβ3 integrin ligand.

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Cyclopropane pipecolic acids a ...... de as an αvβ3 integrin ligand.

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P1476

Cyclopropane pipecolic acids a ...... de as an αvβ3 integrin ligand.

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P2093

Antonio Guarna

http://www.w3.org/2001/XMLSchema#string

Francesca Bianchini

http://www.w3.org/2001/XMLSchema#string

Lorenzo Sernissi

http://www.w3.org/2001/XMLSchema#string

Martina Petrović

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

Stereoselective cyclopropanation reactions

Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins

Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor

A Total Synthesis of FK-506(1).

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists.

Alkyl Substituent Effects on Pipecolyl Amide Isomer Equilibrium: Efficient Methodology for Synthesizing Enantiopure 6-Alkylpipecolic Acids and Conformational Analysis of Their N-Acetyl N'-Methylamides.

Discovery of subnanomolar arginine-glycine-aspartate-based alphaVbeta3/alphaVbeta5 integrin binders embedding 4-aminoproline residues.

Solid-phase guanidinylation as a diversification strategy of poly-L-proline type II peptide mimic scaffolds.

Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids.

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11187-11203

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scholarly article

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10.1002/CHEM.201403077

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English

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A Trabocchi

Dina Scarpi

Ernesto G. Occhiato

P577

2014-07-28T00:00:00Z

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P698

25069617

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Cyclopropane pipecolic acids as templates for linear and cyclic peptidomimetics: application in the synthesis of an Arg-Gly-Asp (RGD)-containing peptide as an αvβ3 integrin ligand.

about

P2860

P2860

Cyclopropane pipecolic acids as templates for linear and cyclic peptidomimetics: application in the synthesis of an Arg-Gly-Asp (RGD)-containing peptide as an αvβ3 integrin ligand.

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