Pyrvinium attenuates Hedgehog signaling downstream of smoothened. - Wikidata - wikimedia - TriplyDB

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

http://www.wikidata.org/entity/Q38978119

about

The hedgehog pathway in triple-negative breast cancer DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance Synthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration Targeting of Wnt/β-Catenin by Anthelmintic Drug Pyrvinium Enhances Sensitivity of Ovarian Cancer Cells to Chemotherapy.Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma The novel role of pyrvinium in cancer therapy.Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity.Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.Synergy between pyrvinium pamoate and azoles against Exophiala dermatitidis.Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.Casein kinase 1α: biological mechanisms and theranostic potential.

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P2860

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

http://www.wikidata.org/entity/Q38978119

description

2014 nî lūn-bûn

@nan

2014年の論文

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2014年学术文章

@wuu

2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

@zh-sg

2014年學術文章

@yue

2014年學術文章

@zh

2014年學術文章

@zh-hant

name

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

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type

label

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

@en

prefLabel

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

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0008-5472.CAN-14-0317

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Cancer Research

P1476

Pyrvinium attenuates Hedgehog signaling downstream of smoothened

@en

P2093

Anthony J Capobianco

http://www.w3.org/2001/XMLSchema#string

Baolin Wang

http://www.w3.org/2001/XMLSchema#string

Brian Hang

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Colin A Flaveny

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Darren Orton

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David J Robbins

http://www.w3.org/2001/XMLSchema#string

Dennis Liang Fei

http://www.w3.org/2001/XMLSchema#string

Ethan Lee

http://www.w3.org/2001/XMLSchema#string

Feng Bai

http://www.w3.org/2001/XMLSchema#string

Lu Han

http://www.w3.org/2001/XMLSchema#string

P2860

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

Altered neural cell fates and medulloblastoma in mouse patched mutants

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4811-4821

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scholarly article

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10.1158/0008-5472.CAN-14-0317

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17

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74

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Jezabel Rodriguez-Blanco

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2014-07-03T00:00:00Z

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263709229

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24994715

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4321822

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