Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
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Stem cell-derived liver cells for drug testing and disease modelingPluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineeringWhole genome transcript profiling of drug induced steatosis in rats reveals a gene signature predictive of outcomeDifferences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary HepatocytesPatient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicityA multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicityRecombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived HepatocytesNew markers for tracking endoderm induction and hepatocyte differentiation from human pluripotent stem cells.Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer.Cell sources for in vitro human liver cell culture models.Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells.Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.Towards Creating the Perfect In Vitro Cell Model.Opportunities and challenges in using human hepatocytes in cytochromes P450 induction assays.Concise Review: Advances in Generating Hepatocytes from Pluripotent Stem Cells for Translational Medicine.High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis.Toxicity testing and drug screening using iPSC-derived hepatocytes, cardiomyocytes, and neural cells.One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells.Prospects and Frontiers of Stem Cell ToxicologyThree-dimensional co-culture of human hepatocytes and mesenchymal stem cells: improved functionality in long-term bioreactor cultures.Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.Human induced pluripotent stem cell-derived hepatocytes for toxicology testing.A transcriptomic study suggesting human iPSC-derived hepatocytes potentially offer a better in vitro model of hepatotoxicity than most hepatoma cell lines.Current Perspectives Regarding Stem Cell-Based Therapy for Liver Cirrhosis.Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes.Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives
P2860
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P2860
Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
@wuu
2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-my
2014年学术文章
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2014年學術文章
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2014年學術文章
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2014年學術文章
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name
Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
@en
type
label
Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
@en
prefLabel
Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
@en
P2093
P356
P1476
Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
@en
P2093
Anna-Karin Sjögren
Gustav Holmgren
Jane Synnergren
Josefina Edsbagge
Magnus Ingelman-Sundberg
Peter Sartipy
Petter Björquist
Tommy B Andersson
P304
P356
10.1124/DMD.114.059154
P577
2014-06-30T00:00:00Z