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The Tip of the Iceberg: Clinical Implications of Genomic Sequencing Projects in Head and Neck CancerMediator kinase module and human tumorigenesisCombination therapeutics in complex diseasesOmics-based identification of biomarkers for nasopharyngeal carcinomaSomatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Mutations of Chromatin Structure Regulating Genes in Human Malignancies.The protein level and transcription activity of activating transcription factor 1 is regulated by prolyl isomerase Pin1 in nasopharyngeal carcinoma progression.Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutationsOncogenic induction of cellular high CpG methylation by Epstein-Barr virus in malignant epithelial cellsModulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damageIntegrated genomic analysis suggests MLL3 is a novel candidate susceptibility gene for familial nasopharyngeal carcinoma.Chloroquine Sensitizes Nasopharyngeal Carcinoma Cells but Not Nasoepithelial Cells to Irradiation by Blocking AutophagyA single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma5-hydroxymethylation of the EBV genome regulates the latent to lytic switch.High expression of Sox10 correlates with tumor aggressiveness and poor prognosis in human nasopharyngeal carcinoma.Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinomaUBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathwayLong-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma.PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survivalWhole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma.HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma.Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma.The role of Epstein-Barr virus in epithelial malignancies.The role of Epstein-Barr virus infection in the pathogenesis of nasopharyngeal carcinoma.Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas.Prevalent somatic BRCA1 mutations shape clinically relevant genomic patterns of nasopharyngeal carcinoma in Southeast Europe.Mutation Clusters from Cancer Exome.Nutlin-3, A P53-Mdm2 Antagonist For Nasopharyngeal Carcinoma Treatment.Investigational drugs for nasopharyngeal carcinoma.Nasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis.Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-Specific Differences.Long noncoding RNA-LET, which is repressed by EZH2, inhibits cell proliferation and induces apoptosis of nasopharyngeal carcinoma cell.The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform.Transcriptome meta-analysis reveals dysregulated pathways in nasopharyngeal carcinoma.Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes.Epstein-Barr virus: more than 50 years old and still providing surprises.Epstein-Barr virus infection and nasopharyngeal carcinoma.Comprehensive genomic profiling of different subtypes of nasopharyngeal carcinoma reveals similarities and differences to guide targeted therapy.Novel biomarkers of nasopharyngeal carcinoma metastasis risk identified by reverse phase protein array based tumor profiling with consideration of plasma Epstein-Barr virus DNA load.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
The genomic landscape of nasopharyngeal carcinoma.
@en
type
label
The genomic landscape of nasopharyngeal carcinoma.
@en
prefLabel
The genomic landscape of nasopharyngeal carcinoma.
@en
P2093
P50
P356
P1433
P1476
The genomic landscape of nasopharyngeal carcinoma.
@en
P2093
Ana Maria Varela
Arjun Sharma
Bengt Fredrik Petersson
Boon Cher Goh
Chan Soh Ha
Feng Gang Yu
H Phillip Koeffler
Henry Yang
Kwok Seng Loh
Li-Zhen Liu
P2888
P304
P356
10.1038/NG.3006
P407
P577
2014-06-22T00:00:00Z