A GMP-compliant protocol to expand and transfect cancer patient T cells with mRNA encoding a tumor-specific chimeric antigen receptor.
about
Strategies to genetically engineer T cells for cancer immunotherapy.Human adenovirus-specific γ/δ and CD8+ T cells generated by T-cell receptor transfection to treat adenovirus infection after allogeneic stem cell transplantation.Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT CellsChimeric antigen receptor-engineered T cells for the treatment of metastatic prostate cancer.Co-Expansion of Cytokine-Induced Killer Cells and Vγ9Vδ2 T Cells for CAR T-Cell Therapy.Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP for clinical research.Adoptive therapy with CAR redirected T cells: the challenges in targeting solid tumors.A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cellsSpotlight on chimeric antigen receptor engineered T cell research and clinical trials in China.Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone.Messenger RNA encoding constitutively active Toll-like receptor 4 enhances effector functions of human T cells.Generation of CD8(+) T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy.Site-specific integration of CAR gene into Jurkat T cells with a linear close-ended AAV-based DNA vector for CAR-T engineering.RNA-transfection of γ/δ T cells with a chimeric antigen receptor or an α/β T-cell receptor: a safer alternative to genetically engineered α/β T cells for the immunotherapy of melanoma.Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins.The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma
P2860
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P2860
A GMP-compliant protocol to expand and transfect cancer patient T cells with mRNA encoding a tumor-specific chimeric antigen receptor.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
A GMP-compliant protocol to ex ...... fic chimeric antigen receptor.
@en
type
label
A GMP-compliant protocol to ex ...... fic chimeric antigen receptor.
@en
prefLabel
A GMP-compliant protocol to ex ...... fic chimeric antigen receptor.
@en
P2093
P2860
P1476
A GMP-compliant protocol to ex ...... fic chimeric antigen receptor.
@en
P2093
Beatrice Schuler-Thurner
Christian Krug
Gerold Schuler
Hinrich Abken
Manuel Wiesinger
P2860
P2888
P304
P356
10.1007/S00262-014-1572-5
P577
2014-06-18T00:00:00Z
P5875
P6179
1038208873