about
Dusquetide: Reduction in oral mucositis associated with enduring ancillary benefits in tumor resolution and decreased mortality in head and neck cancer patients.Blocking autophagy improves the anti-tumor activity of afatinib in lung adenocarcinoma with activating EGFR mutations in vitro and in vivo.p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.Osteosarcoma: Molecular Pathogenesis and iPSC Modeling.Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress.Molecular definitions of autophagy and related processes.Expanding perspectives on the significance of mitophagy in cancer.Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome.Metabolic Interactions in the Tumor Microenvironment.Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway.Acidic pH environment induces autophagy in osteoblasts.Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1.ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma.The Role of Autophagy in Critical Illness-induced Liver Damage.Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells.Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma.Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis.Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice.Lipotoxicity induces hepatic protein inclusions through TBK1-mediated p62/SQSTM1 phosphorylation.DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma.Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways.The protease inhibitor E64d improves ox-LDL-induced endothelial dysfunction in human aortic endothelial cells.Cyanidin suppresses autophagic activity regulating chondrocyte hypertrophic differentiation.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death.Degradation of maternal factors during preimplantation embryonic development.An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor.Love laughs at Locksmiths: Ubiquitylation of p62 unlocks its autophagy receptor potential.Till Death Do Us Part: The Marriage of Autophagy and Apoptosis.Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence.An autophagy-related gene expression signature for survival prediction in multiple cohorts of hepatocellular carcinoma patients.CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer.Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulationAutophagy Is Indispensable for the Self-Renewal and Quiescence of Ovarian Cancer Spheroid Cells with Stem Cell-Like PropertiesZZ-dependent regulation of p62/SQSTM1 in autophagy
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
p62 in Cancer: Signaling Adaptor Beyond Autophagy
@en
type
label
p62 in Cancer: Signaling Adaptor Beyond Autophagy
@en
prefLabel
p62 in Cancer: Signaling Adaptor Beyond Autophagy
@en
P2860
P1433
P1476
p62 in Cancer: Signaling Adaptor Beyond Autophagy
@en
P2093
Jorge Moscat
Maria T Diaz-Meco
P2860
P304
P356
10.1016/J.CELL.2016.09.030
P407
P577
2016-10-01T00:00:00Z