Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells. - Wikidata - wikimedia - TriplyDB

Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells.

Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells.

http://www.wikidata.org/entity/Q39002543

about

The environment of regulatory T cell biology: cytokines, metabolites, and the microbiome Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting Regulatory T-Cell-Mediated Suppression of Conventional T-Cells and Dendritic Cells by Different cAMP Intracellular Pathways The potential of tumor-derived exosomes for noninvasive cancer monitoring The role of regulatory T cells in cancer immunology Tumor-Derived Exosomes and Their Role in Tumor-Induced Immune Suppression Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions.Ecto-nucleotidases activities in the contents of ovarian endometriomas: potential biomarkers of endometriosis Big opportunities for small molecules in immuno-oncology.Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice.Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct manners Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance 1α,25-dihydroxyvitamin D3 acts via transforming growth factor-β to up-regulate expression of immunosuppressive CD73 on human CD4+ Foxp3- T cells Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.Overexpression of CD39 and high tumoral CD39⁺/CD8⁺ ratio are associated with adverse prognosis in resectable gastric cancer Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets.Human ectonucleotidase-expressing CD25(high) Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions.Anti-CD73 in cancer immunotherapy: awakening new opportunities.Exosomes and tumor-mediated immune suppression.Induced regulatory T cells in inhibitory microenvironments created by cancer.Clinical Impact of Regulatory T cells (Treg) in Cancer and HIV.Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function.Tumor-Derived Exosomes and Their Role in Cancer Progression.The Uptake of Extracellular Vesicles is Affected by the Differentiation Status of Myeloid Cells.A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer.Adenosine production: a common path for mesenchymal stem-cell and regulatory T-cell-mediated immunosuppression.Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression.The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.Exosomes carrying immunoinhibitory proteins and their role in cancer.Targeting adenosine in cancer immunotherapy: a review of recent progress.Tr1-Like T Cells - An Enigmatic Regulatory T Cell Lineage High expression of CD39 in gastric cancer reduces patient outcome following radical resection Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia.The effect of tumor-derived exosomes on immune regulation and cancer immunotherapy.The Dual Role of Treg in Cancer.Human adenosine deaminases ADA1 and ADA2 bind to different subsets of immune cells.Exosomes in Cancer: Another Mechanism of Tumor-Induced Immune Suppression.The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma.Separation of plasma-derived exosomes into CD3(+) and CD3(-) fractions allows for association of immune cell and tumor cell markers with disease activity in HNSCC patients.Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells.

P2860

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P2860

Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells.

http://www.wikidata.org/entity/Q39002543

description

2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@en

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@nl

type

label

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@en

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@nl

prefLabel

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@en

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@nl

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Clinical and Experimental Immunology

P1476

Human CD4+ CD39+ regulatory T ...... CD73+ exosomes or CD73+ cells.

@en

P2093

C-S Hong

http://www.w3.org/2001/XMLSchema#string

D Cheng

http://www.w3.org/2001/XMLSchema#string

D G Gillespie

http://www.w3.org/2001/XMLSchema#string

E K Jackson

http://www.w3.org/2001/XMLSchema#string

L Muller

http://www.w3.org/2001/XMLSchema#string

M Harasymczuk

http://www.w3.org/2001/XMLSchema#string

M Mandapathil

http://www.w3.org/2001/XMLSchema#string

P J Schuler

http://www.w3.org/2001/XMLSchema#string

S Lang

http://www.w3.org/2001/XMLSchema#string

T L Whiteside

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P2860

Direct association of adenosine deaminase with a T cell activation antigen, CD26

CD73-generated adenosine: orchestrating the tumor-stroma interplay to promote cancer growth

Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution

Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5'-nucleotidase (CD73)

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.

A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells.

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis.

Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.

High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population

Immunity, inflammation and cancer: a leading role for adenosine.

P304

531-543

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scholarly article

P356

10.1111/CEI.12354

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P433

2

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P478

177

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P577

2014-08-01T00:00:00Z

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261767661

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24749746

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4226604

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