Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.
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ROS and ROS-Mediated Cellular SignalingMitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegansTouch and go: nuclear proteolysis in the regulation of metabolic genes and cancerControl of mitochondrial biogenesis and function by the ubiquitin-proteasome systemmtDNA germ line variation mediated ROS generates retrograde signaling and induces pro-cancerous metabolic featuresDocosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin-proteasome system.Ethanol-induced differential gene expression and acetyl-CoA metabolism in a longevity model of the nematode Caenorhabditis elegans.Proteasomes, Sir2, and Hxk2 form an interconnected aging network that impinges on the AMPK/Snf1-regulated transcriptional repressor Mig1.Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregationhecd-1 modulates notch activity in Caenorhabditis elegans.The role of mitochondrial DNA mutation on neurodegenerative diseases.Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant UbiquitinEvolved genetic and phenotypic differences due to mitochondrial-nuclear interactions.Regulation of the MEI-1/MEI-2 Microtubule-Severing Katanin Complex in Early Caenorhabditis elegans Development.Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.Pharmacologic modeling of primary mitochondrial respiratory chain dysfunction in zebrafish.Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.Soluble Uric Acid Activates the NLRP3 Inflammasome.Activity-Based Probes for HECT E3 Ubiquitin LigasesEffects and mechanisms of prolongevity induced by Lactobacillus gasseri SBT2055 in Caenorhabditis elegans.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.PERM Hypothesis: The Fundamental Machinery Able to Elucidate the Role of Xenobiotics and Hormesis in Cell Survival and HomeostasisDDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania.A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell deathAmyloid-β peptide-induced cytotoxicity and mitochondrial dysfunction in yeast.Coenzyme Q regulates the expression of essential genes of the pathogen- and xenobiotic-associated defense pathway in C. elegans.Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity.Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice.The ubiquitin-proteasome system and autophagy are defective in the taurine-deficient heart.Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging.Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases.
P2860
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P2860
Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@en
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@nl
type
label
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@en
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@nl
prefLabel
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@en
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@nl
P2093
P50
P1433
P1476
Pathogenesis of human mitochon ...... e ubiquitin/proteasome system.
@en
P2093
Alexandra Segref
Johannes Mansfeld
Nurit Livnat-Levanon
Regina Ensenauer
P304
P356
10.1016/J.CMET.2014.01.016
P577
2014-04-01T00:00:00Z