about
Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents.Sulfinate derivatives: dual and versatile partners in organic synthesis.Palladium-Catalyzed One-Pot Reaction of Hydrazones, Dihaloarenes, and Organoboron Reagents: Synthesis and Cytotoxic Activity of 1,1-Diarylethylene Derivatives.Tandem one-pot palladium-catalyzed coupling of hydrazones, haloindoles, and amines: synthesis of amino-N-vinylindoles and their effect on human colon carcinoma cells.Reversion of apoptotic resistance of TP53-mutated Burkitt lymphoma B-cells to spindle poisons by exogenous activation of JNK and p38 MAP kinases.Discovery and hit to lead optimization of novel combretastatin A-4 analogues: dependence of C-linker length and hybridization.An efficient coupling of N-tosylhydrazones with 2-halopyridines: synthesis of 2-α-styrylpyridines endowed with antitumor activity.Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs.Synthesis, biological evaluation, and structure-activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors.Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: synthesis, cytotoxicity and antitubulin activity.B-ring-modified isocombretastatin A-4 analogues endowed with interesting anticancer activities.Synthesis, biological evaluation and molecular modeling studies of imidazo[1,2-a]pyridines derivatives as protein kinase inhibitors.Discovery of isoerianin analogues as promising anticancer agents.Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: an easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4.Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents.Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent.Exploration of potential prodrug approach of the bis-thiazolium salts T3 and T4 for orally delivered antimalarials.Synthesis of various 3-substituted 1,2,4-oxadiazole-containing chiral beta 3- and alpha-amino acids from Fmoc-protected aspartic acid.Synthesis of ortho/ortho'-substituted 1,1-diarylethylenes through cross-coupling reactions of sterically encumbered hydrazones and aryl halides.Solid-phase synthesis of arginine-containing peptides and fluorogenic substrates using a side-chain anchoring approach.Csp2-N bond formation via ligand-free Pd-catalyzed oxidative coupling reaction of N-tosylhydrazones and indole derivatives.Palladium-catalyzed Markovnikov terminal arylalkynes hydrostannation: application to the synthesis of 1,1-diarylethylenes.Mono- and bis-thiazolium salts have potent antimalarial activity.Synthesis and antitumor activity of benzils related to combretastatin A-4.A general synthesis of arylindoles and (1-arylvinyl)carbazoles via a one-pot reaction from N-tosylhydrazones and 2-nitro-haloarenes and their potential application to colon cancer.Csp2-Csp2 and Csp2-N Bond Formation in a One-Pot Reaction between N-Tosylhydrazones and Bromonitrobenzenes: An Unexpected Cyclization to Substituted Indole Derivatives.Selective Metal-Free Deoxygenation of Unsymmetrical 1,2-Dicarbonyl Compounds by Chlorotrimethylsilane and Sodium Iodide.Cyclic Peptides with a Diversely Substituted Guanidine Bridge: Solid-Phase Synthesis and Structural AnalysisSolid-phase synthesis of dipeptidic and pseudo-dipeptidic potential NOS inhibitors through a side-chain anchoring approachSolid phase synthesis of mono- or disubstituted arginine containing peptides from an isothiocitrulline precursorSynthesis of (R) and (S) enantiomers of Fmoc-protected 1,2,4-oxadiazole-containing β3-amino acids from Fmoc-(R)-β-HAsp(OtBu)-OHDesign and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4Regiocontrol of the palladium-catalyzed tin hydride addition to Z-enynols: remarkable Z-directing effectsPlatinum oxide catalyzed hydrosilylation of unsymmetrical internal aryl alkynes under ortho-substituent regiocontrolPlatinum oxide catalyzed silylation of aryl halides with triethylsilane: an efficient synthetic route to functionalized aryltriethylsilanesSynthesis of 1,1-diarylethylenes via efficient iron/copper co-catalyzed coupling of 1-arylvinyl halides with Grignard reagentsCopper-catalyzed reductive coupling of tosylhydrazones with amines: a convenient route to α-branched aminesPd-catalyzed reaction of sterically hindered hydrazones with aryl halides: synthesis of tetra-substituted olefins related to iso-combretastatin A4Catalytic three-component one-pot reaction of hydrazones, dihaloarenes, and aminesStereoretentive palladium-catalyzed arylation, alkenylation, and alkynylation of 1-thiosugars and thiols using aminobiphenyl palladacycle precatalyst at room temperature
P50
Q35531648-44AA74EB-0A2F-4EF8-BEE5-A0B9DA2CEC7DQ38263672-C4AD3547-2D40-4119-B3AC-D39319548416Q38868273-A2E318DA-9FDE-4526-911F-AFC132DED18DQ38974860-9894B967-2385-476B-9FCF-6C7C873B7CDAQ38999750-B7DFC8DE-886C-4044-90DD-FBE9DECB6D94Q39059474-FB3EEE3B-8220-4510-AD2E-B80E0FE48631Q39161057-D38B8729-A695-460D-A1E6-31C5B2E474D7Q39204088-3D736D67-44BA-4454-B6E7-04E0AC0D75F3Q39263355-138373B8-A199-4868-B008-8860DF13F7A7Q39373765-7028B5C8-9207-459A-B16F-4397A71ADDBFQ39459714-D5EB4E61-1DF2-443E-9068-3D42CC1EB713Q39542938-1843C18A-A32D-4F6D-9BE3-BE38C7EB2D1EQ39584180-05CA3310-2EDB-4BD1-ABEB-122050ACB626Q39680777-0168E326-A316-4265-9F62-762603B58B88Q39793470-ACE4A11D-4CE8-4130-866A-65F32785A780Q39837366-EAF00035-5BAE-4A2A-B6B4-7E4736B2B4B6Q42982619-83E489F3-1E45-4F20-8212-41AF9463C3FDQ44581362-FD7C4549-6D73-4AE4-A2C6-4FB0B99BBF52Q44737417-946A493E-C8AB-4F5E-8FE0-E9D11C4AD091Q45154265-F1B6E6AA-F43C-49AA-A93C-6C13D374A384Q45939982-70DFE64A-A5EF-436B-8D15-7B43A1A7E8D0Q46204011-BD71E1B8-4500-4789-9FCD-E1682128CB10Q46485532-7BCECB64-49D7-44EE-A38E-5EE92AF0FAC9Q46597888-88436AC7-3FE8-419C-959F-EAED179D137DQ48272373-BA605194-7F26-4AA2-B32B-637F77DC6F10Q52741562-6B9A1FE1-C553-4D9F-AC84-444542570893Q53075113-5AE532FA-8071-4505-A5EF-9DEBF07C31F2Q58101186-2C3E9D00-6455-4F25-B000-496B37388AF6Q58101977-B0D3F332-4D85-44B8-B1E7-5FE9F02D2D9FQ58102939-D9D8DB48-6F51-4493-BE30-AB0AA0C4E385Q58103229-2C94C393-6EEF-48D6-A7E4-543A463E67B7Q61835175-5BCF8035-059C-43C3-BB07-96922B18A839Q80155573-A8DF45A6-4609-41C6-8135-2AB118CF6480Q81559707-53898997-663D-4229-B0AC-4C81F6100AD0Q82631762-064B6F91-D8C9-46ED-B765-809DC0BD397DQ84194022-6A1F07D2-1F3A-469B-9E42-1A9EAA1E49E5Q84605994-18047C15-D13A-40FE-8BF5-0DFD526440BAQ84769362-21CC7DD8-D45B-4AE9-BB56-5C39FEFEB697Q85719820-E3877D29-BDE7-45BD-BD1B-EA3FD642CED5Q87119594-65AEC7BD-37AA-455F-89DA-2AF38910B1FA
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Abdallah Hamze
@ast
Abdallah Hamze
@en
Abdallah Hamze
@es
Abdallah Hamze
@nl
Abdallah Hamze
@sl
type
label
Abdallah Hamze
@ast
Abdallah Hamze
@en
Abdallah Hamze
@es
Abdallah Hamze
@nl
Abdallah Hamze
@sl
prefLabel
Abdallah Hamze
@ast
Abdallah Hamze
@en
Abdallah Hamze
@es
Abdallah Hamze
@nl
Abdallah Hamze
@sl
P1053
A-9738-2013
P106
P1153
10339982700
P21
P31
P3829
P496
0000-0001-8425-1971