Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.
about
One-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingNon-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer MetabolismOncogenes strike a balance between cellular growth and homeostasisFolliculin regulates ampk-dependent autophagy and metabolic stress survivalDissecting the Dual Role of AMPK in Cancer: From Experimental to Human StudiesA New Combinatorial Optimization Approach for Integrated Feature Selection Using Different Datasets: A Prostate Cancer Transcriptomic StudyIdentification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus.Role of YY1 in the pathogenesis of prostate cancer and correlation with bioinformatic data sets of gene expressionRegulation of the pentose phosphate pathway by an androgen receptor-mTOR-mediated mechanism and its role in prostate cancer cell growth.Dissecting the role of AMP-activated protein kinase in human diseases.The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels.Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer.Is 5´-AMP-Activated Protein Kinase Both Jekyll and Hyde in Bladder Cancer?Silencing of PMEPA1 accelerates the growth of prostate cancer cells through AR, NEDD4 and PTEN.Regulation of Androgen Receptor Expression Alters AMPK Phosphorylation in the Endometrium: In Vivo and In Vitro Studies in Women with Polycystic Ovary Syndrome.AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.Testosterone Replacement Modulates Cardiac Metabolic Remodeling after Myocardial Infarction by Upregulating PPARα.Preclinical efficacy of growth hormone-releasing hormone antagonists for androgen-dependent and castration-resistant human prostate cancer.Probing the prostate tumour microenvironment II: Impact of hypoxia on a cell model of prostate cancer progression.Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells.The double-edged sword of AMPK signaling in cancer and its therapeutic implications.Targeting the 5'-AMP-activated protein kinase and related metabolic pathways for the treatment of prostate cancer.Metabolomic profiling for the identification of novel diagnostic markers in prostate cancer.Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer.Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts.A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.Glucose Metabolism in the Progression of Prostate Cancer.PGC-1 Coactivators: Shepherding the Mitochondrial Biogenesis of Tumors.The Metabolic Phenotype of Prostate Cancer.Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism.Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism.Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade.Metformin directly acts on mitochondria to alter cellular bioenergetics.Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells.Stable isotope tracer analysis in isolated mitochondria from mammalian systems.Transcriptomic analysis reveals inhibition of androgen receptor activity by AMPK in prostate cancer cells.Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression.The Glycolytic Switch in Tumors: How Many Players Are Involved?
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P2860
Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Androgens regulate prostate ca ...... -1α-mediated metabolic switch.
@en
Androgens regulate prostate ca ...... -1α-mediated metabolic switch.
@nl
type
label
Androgens regulate prostate ca ...... -1α-mediated metabolic switch.
@en
Androgens regulate prostate ca ...... -1α-mediated metabolic switch.
@nl
prefLabel
Androgens regulate prostate ca ...... -1α-mediated metabolic switch.
@en
Androgens regulate prostate ca ...... -1α-mediated metabolic switch.
@nl
P2093
P2860
P50
P356
P1433
P1476
Androgens regulate prostate ca ...... C-1α-mediated metabolic switch
@en
P2093
J B Tennakoon
M M Ittmann
O R Ilkayeva
P2860
P2888
P304
P356
10.1038/ONC.2013.463
P407
P577
2013-11-04T00:00:00Z