about
Dynamics and Cleavability at the alpha-cleavage site of APP(684-726) in different lipid environmentsP-Glycoprotein in cell cultures: a combined approach to study expression, localisation, and functionality in the confocal microscope.FDG kinetic modeling in small rodent brain PET: optimization of data acquisition and analysisNo entry for TAT(44-57) into liposomes and intact MDCK cells: novel approach to study membrane permeation of cell-penetrating peptides.Effect of the modulation of the membrane lipid composition on the localization and function of P-glycoprotein in MDR1-MDCK cells.MDCK cell cultures as an epithelial in vitro model: cytoskeleton and tight junctions as indicators for the definition of age-related stages by confocal microscopy.The biochemistry of drug metabolism--an introduction: Part 2. Redox reactions and their enzymes.The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.The biochemistry of drug metabolism--an introduction: part 6. Inter-individual factors affecting drug metabolism.The biochemistry of drug metabolism--an introduction: part 5. Metabolism and bioactivity.The biochemistry of drug metabolism--an introduction: part 1. Principles and overview.Cell cultures as tools in biopharmacy.Permeation of aromatic carboxylic acids across lipid bilayers: the pH-partition hypothesis revisitedAccurate molecular imaging of small animals taking into account animal models, handling, anaesthesia, quality control and imaging system performancePreclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis.Synthesis and preclinical evaluation of a new C-6 alkylated pyrimidine derivative as a PET imaging agent for HSV1-tk gene expression.Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering.The biochemistry of drug metabolism--an introduction: part 7. Intra-individual factors affecting drug metabolism.Lipid-bilayer permeation of drug-like compounds.Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition.Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor.Evidence-based approach to assess passive diffusion and carrier-mediated drug transport.Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition.When barriers ignore the "rule-of-five".Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging.Quantitative aspects of drug permeation across in vitro and in vivo barriers.Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability.Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging.GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET.Synthesis and biological evaluation of (18)F-labeled Fluoroethoxy tryptophan analogues as potential PET tumor imaging agents.Synthesis and preliminary biological evaluation of O-2((2-[(18)F]fluoroethyl)methylamino)ethyltyrosine ([(18)F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging.Imaging tumour ATB0,+ transport activity by PET with the cationic amino acid O-2((2-[18F]fluoroethyl)methyl-amino)ethyltyrosine.Synthesis and biological evaluation of ¹⁸F-labeled fluoropropyl tryptophan analogs as potential PET probes for tumor imaging.Characterization of different osteosarcoma phenotypes by PET imaging in preclinical animal models.Radiolabeling and in vitro /in vivo evaluation of N-(1-adamantyl)-8-methoxy-4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxamide as a PET probe for imaging cannabinoid type 2 receptor.Development and evaluation of novel PET tracers for imaging cannabinoid receptor type 2 in brain.Radiosynthesis and preclinical evaluation of 3'-Aza-2'-[(18)F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting.Radiofluorinated histamine H₃ receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation.5-(2-18F-fluoroethoxy)-L-tryptophan as a substrate of system L transport for tumor imaging by PET.In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5).
P50
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P50
description
hulumtuese
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researcher
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հետազոտող
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name
Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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type
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D. Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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Stefanie D Krämer
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P1006
P214
P244
P1006
P106
P108
P21
P214
P244
nb2008005574
P31
P496
0000-0002-0426-4340
P735
P7859
lccn-nb2008005574