Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells.
about
Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?Uncoupling protein-2 mediates the protective action of berberine against oxidative stress in rat insulinoma INS-1E cells and in diabetic mouse islets.Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes.Hepcidin links gluco-toxicity to pancreatic beta cell dysfunction by inhibiting Pdx-1 expression.Serotonin- and Dopamine-Related Gene Expression in db/db Mice Islets and in MIN6 β-Cells Treated with Palmitate and Oleate.Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells.Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release.Energy depletion and not ROS formation is a crucial step of glucolipotoxicity (GLTx) in pancreatic beta cells.Plasma vascular endothelial growth factor B levels are increased in patients with newly diagnosed type 2 diabetes mellitus and associated with the first phase of glucose-stimulated insulin secretion function of β-cell.Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation.
P2860
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P2860
Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
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2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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2013年论文
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2013年论文
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name
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@en
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@nl
type
label
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@en
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@nl
prefLabel
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@en
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@nl
P2860
P356
P1433
P1476
Novel insights into pancreatic ...... sm in INS-1E insulinoma cells.
@en
P2093
Jonathan Barlow
P2860
P304
P356
10.1042/BJ20131002
P407
P577
2013-12-01T00:00:00Z