Mutations in the TAR hairpin affect the equilibrium between alternative conformations of the HIV-1 leader RNA
about
Identification of a minimal region of the HIV-1 5'-leader required for RNA dimerization, NC binding, and packagingRegulated HIV-2 RNA dimerization by means of alternative RNA conformations.Dimerization of retroviral RNA genomes: an inseparable pair.Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA.Translational control of retroviruses.Functional analysis of the complex trans-activating response element RNA structure in simian immunodeficiency virus.In vitro evidence that the untranslated leader of the HIV-1 genome is an RNA checkpoint that regulates multiple functions through conformational changes.The in vitro loose dimer structure and rearrangements of the HIV-2 leader RNA.A short sequence motif in the 5' leader of the HIV-1 genome modulates extended RNA dimer formation and virus replication.Prediction of conserved long-range RNA-RNA interactions in full viral genomes.The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycleA riboswitch regulates RNA dimerization and packaging in human immunodeficiency virus type 1 virions.Minimal region sufficient for genome dimerization in the human immunodeficiency virus type 1 virion and its potential roles in the early stages of viral replication.Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape.A Phylogenetic Survey on the Structure of the HIV-1 Leader RNA Domain That Encodes the Splice Donor SignalProbing alternative foldings of the HIV-1 leader RNA by antisense oligonucleotide scanning arrays.A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect.Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA.The TAR hairpin of human immunodeficiency virus type 1 can be deleted when not required for Tat-mediated activation of transcription.A novel long distance base-pairing interaction in human immunodeficiency virus type 1 RNA occludes the Gag start codon.The availability of the primer activation signal (PAS) affects the efficiency of HIV-1 reverse transcription initiation.Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription
P2860
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P2860
Mutations in the TAR hairpin affect the equilibrium between alternative conformations of the HIV-1 leader RNA
description
2001 nî lūn-bûn
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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2001年论文
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2001年论文
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name
Mutations in the TAR hairpin a ...... ations of the HIV-1 leader RNA
@en
Mutations in the TAR hairpin a ...... tions of the HIV-1 leader RNA.
@nl
type
label
Mutations in the TAR hairpin a ...... ations of the HIV-1 leader RNA
@en
Mutations in the TAR hairpin a ...... tions of the HIV-1 leader RNA.
@nl
prefLabel
Mutations in the TAR hairpin a ...... ations of the HIV-1 leader RNA
@en
Mutations in the TAR hairpin a ...... tions of the HIV-1 leader RNA.
@nl
P2860
P356
P1476
Mutations in the TAR hairpin a ...... ations of the HIV-1 leader RNA
@en
P2093
P2860
P304
P356
10.1093/NAR/29.12.2594
P407
P577
2001-06-01T00:00:00Z