CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner. - Wikidata - wikimedia - TriplyDB

CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner.

CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner.

http://www.wikidata.org/entity/Q39098086

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Mucosal-associated invariant T cells in autoimmunity, immune-mediated diseases and airways disease Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out CD1d- and MR1-Restricted T Cells in Sepsis Regulation of Lipid Specific and Vitamin Specific Non-MHC Restricted T Cells by Antigen Presenting Cells and Their Therapeutic Potentials MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response to Mycobacterium tuberculosis MAIT cells are activated during human viral infections MAIT cells: new guardians of the liver Innate-like lymphocytes in intestinal infections MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation Check MAIT.Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver.MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immun Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines.Circulating mucosal associated invariant T cells are activated in Vibrio cholerae O1 infection and associated with lipopolysaccharide antibody responses.Mucosal-associated invariant T-cells: new players in anti-bacterial immunity CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.The rise and fall of MAIT cells with age MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets.Altered CD161 bright CD8+ mucosal associated invariant T (MAIT)-like cell dynamics and increased differentiation states among juvenile type 1 diabetics.Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection.Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation.MAIT cells are activated and accumulated in the inflamed mucosa of ulcerative colitis.Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy Activation, Impaired Tumor Necrosis Factor-α Production, and Deficiency of Circulating Mucosal-Associated Invariant T Cells in Patients with Scrub Typhus.Molecular Analyses Define Vα7.2-Jα33+ MAIT Cell Depletion in HIV Infection: A Case-Control Study.MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications.Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1.Distinct activation thresholds of human conventional and innate-like memory T cells.Human MAIT-cell responses to Escherichia coli: activation, cytokine production, proliferation, and cytotoxicity Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling.Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation.MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection.Steroid-induced Deficiency of Mucosal-associated Invariant T Cells in the Chronic Obstructive Pulmonary Disease Lung. Implications for Nontypeable Haemophilus influenzae Infection.Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells.

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CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner.

http://www.wikidata.org/entity/Q39098086

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CD161++ CD8+ T cells, includin ...... 8 in a TCR-independent manner.

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CD161++ CD8+ T cells, includin ...... 8 in a TCR-independent manner.

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CD161++ CD8+ T cells, includin ...... 8 in a TCR-independent manner.

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CD161++ CD8+ T cells, includin ...... 8 in a TCR-independent manner.

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European Journal of Immunology

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CD161++ CD8+ T cells, includin ...... 8 in a TCR-independent manner.

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Ayako Kurioka

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Catherine de Lara

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Elisabeth Mettke

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Emma Attwod

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James E Ussher

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Jonathan Shadwell

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Matthew Bilton

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Rachel Richardson

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Ted H Hansen

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P2860

Regulation of virus-induced IL-12 and IL-23 expression in human macrophages

Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production

The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice

IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

MR1 presents microbial vitamin B metabolites to MAIT cells

Toll-like receptors

Biochemical features of the MHC-related protein 1 consistent with an immunological function

Cloning of a new cytokine that induces IFN-gamma production by T cells

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195-203

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10.1002/EJI.201343509

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1

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44

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Christian B Willberg

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2013-10-01T00:00:00Z

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256481664

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24019201

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3947164

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