The effect of Cu(2+) and Zn(2+) on the Aβ42 peptide aggregation and cellular toxicity
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Targeting Metal-Aβ Aggregates with Bifunctional Radioligand [(11)C]L2-b and a Fluorine-18 Analogue [(18)F]FL2-bDietary high cholesterol and trace metals in the drinking water increase levels of ABCA1 in the rabbit hippocampus and temporal cortexTruncated Amyloid-β(11-40/42) from Alzheimer Disease Binds Cu2+ with a Femtomolar Affinity and Influences Fiber Assembly.Metabolic relationship between diabetes and Alzheimer's Disease affected by Cyclo(His-Pro) plus zinc treatment.Is interaction of amyloid β-peptides with metals involved in cognitive activity?Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer's Drug Discovery.Relationship between Zinc (Zn (2+) ) and Glutamate Receptors in the Processes Underlying Neurodegeneration.Histidine-Rich Oligopeptides To Lessen Copper-Mediated Amyloid-β Toxicity.Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity.Small bifunctional chelators that do not disaggregate amyloid β fibrils exhibit reduced cellular toxicity.Cross talk between neurometals and amyloidogenic proteins at the synapse and the pathogenesis of neurodegenerative diseases.Divalent copper ion bound amyloid-β(40) and amyloid-β(42) alloforms are less preferred than divalent zinc ion bound amyloid-β(40) and amyloid-β(42) alloforms.Characterization of plasma metal profiles in Alzheimer's disease using multivariate statistical analysisMulti-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's disease.Mutual interference of Cu and Zn ions in Alzheimer's disease: perspectives at the molecular level.New Hydroxyquinoline-Based Derivatives as Potent Modulators of Amyloid-β Aggregations.Coordination Chemistry of Bifunctional Chemical Agents Designed for Applications in 64Cu PET Imaging for Alzheimer's Disease.Evaluation of 64Cu-Based Radiopharmaceuticals that Target Aβ Peptide Aggregates as Diagnostic Tools for Alzheimer's Disease.Neurotoxicity of Zinc.Zinc, Carnosine, and Neurodegenerative Diseases.Cu²⁺ accentuates distinct misfolding of Aβ₁₋₄₀ and Aβ₁₋₄₂ peptides, and potentiates membrane disruption.Azo-dyes based small bifunctional molecules for metal chelation and controlling amyloid formationImplications of Metal Binding and Asparagine Deamidation for Amyloid Formation
P2860
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P2860
The effect of Cu(2+) and Zn(2+) on the Aβ42 peptide aggregation and cellular toxicity
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
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name
The effect of Cu(2+) and Zn(2+) on the Aβ42 peptide aggregation and cellular toxicity
@en
type
label
The effect of Cu(2+) and Zn(2+) on the Aβ42 peptide aggregation and cellular toxicity
@en
prefLabel
The effect of Cu(2+) and Zn(2+) on the Aβ42 peptide aggregation and cellular toxicity
@en
P2093
P2860
P356
P1433
P1476
The effect of Cu(2+) and Zn(2+) on the Aβ42 peptide aggregation and cellular toxicity
@en
P2093
Anuj K Sharma
Jaekwang Kim
Jungsu Kim
Liviu M Mirica
Stephanie T Pavlova
P2860
P304
P356
10.1039/C3MT00161J
P577
2013-11-01T00:00:00Z