A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis.
about
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayPromiscuous DNA synthesis by human DNA polymerase θDNA polymerase family X: function, structure, and cellular rolesIncreased learning and brain long-term potentiation in aged mice lacking DNA polymerase μMolecular Dynamics Simulations and Structural Analysis to Decipher Functional Impact of a Twenty Residue Insert in the Ternary Complex of Mus musculus TdT IsoformStructural insight into the substrate specificity of DNA Polymerase muStructure of a NHEJ polymerase-mediated DNA synaptic complexMolecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA PolymeraseSustained active site rigidity during synthesis by human DNA polymerase μStructures of the Leishmania infantum polymerase betaXRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gapsEnd-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joiningFlexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune systemNonhomologous end joining: a good solution for bad endsModeling DNA polymerase μ motions: subtle transitions before chemistry.Essential role for polymerase specialization in cellular nonhomologous end joining.Creative template-dependent synthesis by human polymerase mu.The X family portrait: structural insights into biological functions of X family polymerases.Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joiningA role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo.Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ.Polymerases in nonhomologous end joining: building a bridge over broken chromosomes.DNA polymerases in nonhomologous end joining: are there any benefits to standing out from the crowd?Repair of double-strand breaks by end joining.Break-induced replication links microsatellite expansion to complex genome rearrangements.Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.DNA expansions generated by human Polμ on iterative sequences.DNA-binding determinants promoting NHEJ by human Polμ.Polμ tumor variants decrease the efficiency and accuracy of NHEJ.Conferring a template-dependent polymerase activity to terminal deoxynucleotidyltransferase by mutations in the Loop1 region.Evidence that base stacking potential in annealed 3' overhangs determines polymerase utilization in yeast nonhomologous end joining.Unusual evolution of a catalytic core element in CCA-adding enzymes.Decision-making during NHEJ: a network of interactions in human Polμ implicated in substrate recognition and end-bridging.Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase.
P2860
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P2860
A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis.
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
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2006年论文
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2006年论文
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name
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@en
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@nl
type
label
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@en
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@nl
prefLabel
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@en
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@nl
P2093
P2860
P356
P1476
A specific loop in human DNA p ...... and DNA-instructed synthesis.
@en
P2093
Dale Ramsden
José F Ruiz
Luis Blanco
Raquel Juárez
Stephanie A Nick McElhinny
P2860
P304
P356
10.1093/NAR/GKL457
P407
P577
2006-09-08T00:00:00Z