Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress. - Wikidata - wikimedia - TriplyDB

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress.

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress.

http://www.wikidata.org/entity/Q39123771

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The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration Role of sirtuins in ischemia-reperfusion injury DNA Damage and Pulmonary Hypertension Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease Sirtuins in metabolism, DNA repair and cancer Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study Mitochondrial stress signaling promotes cellular adaptations Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase.BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuins Protective Role of Sirtuin3 (SIRT3) in Oxidative Stress Mediated by Hepatitis B Virus X Protein Expression.Sirtuin regulation in aging and injury Mechanisms and Dynamics of Protein Acetylation in Mitochondria.Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.Roles of NAD (+) , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury.Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia.Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer.Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders Roles of sirtuins in the regulation of antioxidant defense and bioenergetic function of mitochondria under oxidative stress.BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management.Mitochondrial remodeling: Rearranging, recycling, and reprogramming.Mitochondrial Sirtuins in Cancer: Emerging Roles and Therapeutic Potential.Post-translational modifications in mitochondria: protein signaling in the powerhouse.CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance.Sirtuin 3 inhibits hepatocellular carcinoma growth through the glycogen synthase kinase-3β/BCL2-associated X protein-dependent apoptotic pathway.SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis.Beneficial effects of exercise on age-related mitochondrial dysfunction and oxidative stress in skeletal muscle.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage.SIRT3: Oncogene and Tumor Suppressor in Cancer.Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemia.Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice.SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity.The Role of Sirtuins in Antioxidant and Redox Signaling.CREBBP and p300 lysine acetyl transferases in the DNA damage response.Concentration-dependent effect of fumonisin B1 on apoptosis in oesophageal cancer cells.

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P2860

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress.

http://www.wikidata.org/entity/Q39123771

description

2013 nî lūn-bûn

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2013年の論文

@ja

2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Interaction of Sirt3 with OGG1 ...... death under oxidative stress.

@en

Interaction of Sirt3 with OGG1 ...... death under oxidative stress.

@nl

type

label

Interaction of Sirt3 with OGG1 ...... death under oxidative stress.

@en

Interaction of Sirt3 with OGG1 ...... death under oxidative stress.

@nl

prefLabel

Interaction of Sirt3 with OGG1 ...... death under oxidative stress.

@en

Interaction of Sirt3 with OGG1 ...... death under oxidative stress.

@nl

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P1433

Cell Death and Disease

P1476

Interaction of Sirt3 with OGG1 ...... l death under oxidative stress

@en

P2093

A S P Gowda

http://www.w3.org/2001/XMLSchema#string

D Liu

http://www.w3.org/2001/XMLSchema#string

H Wu

http://www.w3.org/2001/XMLSchema#string

J W Yang

http://www.w3.org/2001/XMLSchema#string

J-M Yang

http://www.w3.org/2001/XMLSchema#string

K Huber-Keener

http://www.w3.org/2001/XMLSchema#string

L Zhang

http://www.w3.org/2001/XMLSchema#string

R Patel

http://www.w3.org/2001/XMLSchema#string

X Ren

http://www.w3.org/2001/XMLSchema#string

Y Cheng

http://www.w3.org/2001/XMLSchema#string

P2860

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

Altered sirtuin expression is associated with node-positive breast cancer

SIRT3 and cancer: tumor promoter or suppressor?

SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity

Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice

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e731

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scholarly article

P356

10.1038/CDDIS.2013.254

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P478

4

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Thomas E. Spratt

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2013-07-18T00:00:00Z

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P5875

250919759

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23868064

http://www.w3.org/2001/XMLSchema#string

P921

apoptotic process

mitochondrial DNA

P932

3730425

http://www.w3.org/2001/XMLSchema#string