The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations
about
Targeting BMP signalling in cardiovascular disease and anaemiaThe cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P.Estrogen receptor-dependent attenuation of hypoxia-induced changes in the lung genome of pulmonary hypertension rats.Future breakthroughs in the genetics of pulmonary arterial hypertension.Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.Extracellular processing of the cartilage proteoglycan aggregate and its effect on CD44-mediated internalization of hyaluronanThe genome of the myxosporean Thelohanellus kitauei shows adaptations to nutrient acquisition within its fish host.Mutation in BMPR2 Promoter: A 'Second Hit' for Manifestation of Pulmonary Arterial Hypertension?Endothelial Expression of Endothelin Receptor A in the Systemic Capillary Leak SyndromeThe Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response.The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertensionDownregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug InteractionsTet38 Efflux Pump Affects Staphylococcus aureus Internalization by Epithelial Cells through Interaction with CD36 and Contributes to Bacterial Escape from Acidic and Nonacidic PhagolysosomesDifferential regulation of translation and endocytosis of alternatively spliced forms of the type II bone morphogenetic protein (BMP) receptorBone morphogenetic protein signalling in pulmonary hypertension: advances and therapeutic implications.Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse.The progressive ankylosis protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface.MnTBAP increases BMPR-II expression in endothelial cells and attenuates vascular inflammation.Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier FunctionTranslational Advances in the Field of Pulmonary Hypertension Molecular Medicine of Pulmonary Arterial Hypertension. From Population Genetics to Precision Medicine and Gene Editing.Pharmacological activation of PPARγ inhibits hypoxia-induced proliferation through a caveolin-1 targeted and dependent mechanism in PASMCs.Methods to follow intracellular trafficking of cell-penetrating peptides.Inhibition of endo-lysosomal function exacerbates vascular calcification.The cellular uptake of angiogenin, an angiogenic and neurotrophic factor is through multiple pathways and largely dynamin independent.Recent Advances in Endothelial Colony Forming Cells Toward Their Use in Clinical TranslationExome data clouds the pathogenicity of genetic variants in Pulmonary Arterial Hypertension
P2860
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P2860
The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The lysosomal inhibitor, chlor ...... s harbouring BMPR-II mutations
@en
The lysosomal inhibitor, chlor ...... harbouring BMPR-II mutations.
@nl
type
label
The lysosomal inhibitor, chlor ...... s harbouring BMPR-II mutations
@en
The lysosomal inhibitor, chlor ...... harbouring BMPR-II mutations.
@nl
prefLabel
The lysosomal inhibitor, chlor ...... s harbouring BMPR-II mutations
@en
The lysosomal inhibitor, chlor ...... harbouring BMPR-II mutations.
@nl
P2093
P2860
P356
P1476
The lysosomal inhibitor, chlor ...... s harbouring BMPR-II mutations
@en
P2093
Benjamin J Dunmore
Mark R Toshner
Micheala A Aldred
Paul D Upton
P2860
P304
P356
10.1093/HMG/DDT216
P577
2013-05-12T00:00:00Z