Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.
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Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationDNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceEpigenetic reduction of DNA repair in progression to gastrointestinal cancermiR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB RepairMammalian polymerase θ promotes alternative NHEJ and suppresses recombination2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay.Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damageLentiviral protein delivery of meganucleases in human cells mediates gene targeting and alleviates toxicity.Differences in the recruitment of DNA repair proteins at subtelomeric and interstitial I-SceI endonuclease-induced DNA double-strand breaks.DNA polymerase beta participates in DNA End-joining.BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks.Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas.Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors.DNA repair and cell cycle checkpoint defects in a mouse model of 'BRCAness' are partially rescued by 53BP1 deletion.VX-984 is a selective inhibitor of non-homologous end joining, with possible preferential activity in transformed cells.
P2860
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P2860
Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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name
Development of an assay to mea ...... r activity in mammalian cells.
@en
Development of an assay to mea ...... r activity in mammalian cells.
@nl
type
label
Development of an assay to mea ...... r activity in mammalian cells.
@en
Development of an assay to mea ...... r activity in mammalian cells.
@nl
prefLabel
Development of an assay to mea ...... r activity in mammalian cells.
@en
Development of an assay to mea ...... r activity in mammalian cells.
@nl
P2093
P2860
P356
P1476
Development of an assay to mea ...... r activity in mammalian cells.
@en
P2093
Alexander G Goglia
Maria Jasin
Ranjit S Bindra
Simon N Powell
P2860
P356
10.1093/NAR/GKT255
P407
P577
2013-04-12T00:00:00Z