A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations
about
From receptor binding kinetics to signal transduction; a missing link in predicting in vivo drug-action.Analgosedation in paediatric severe traumatic brain injury (TBI): practice, pitfalls and possibilities.CNS Anticancer Drug Discovery and Development: 2016 conference insights.Predicting Drug Concentration-Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically-Based Pharmacokinetic Model.Development of a Region-Specific Physiologically Based Pharmacokinetic Brain Model to Assess Hippocampus and Frontal Cortex Pharmacokinetics.Novel CNS drug discovery and development approach: model-based integration to predict neuro-pharmacokinetics and pharmacodynamics.Clinical Pharmacokinetics and Pharmacodynamics of Drugs in the Central Nervous System.Modelling the delay between pharmacokinetics and EEG effects of morphine in rats: binding kinetic versus effect compartment modelsFingerprints of CNS drug effects: a plasma neuroendocrine reflection of D receptor activation using multi-biomarker pharmacokinetic/pharmacodynamic modelling
P2860
Q42620551-B07D96D7-D0B7-4E1A-9280-6F8DEB93BF77Q43402385-99F2B01C-BABD-48F1-9C75-EDA0FC8D1C4BQ43772415-441B9F3C-42F9-4133-B215-269991B6BC21Q47131961-EAD78FAC-1743-4050-8A05-B63DDDDE722BQ47860080-F8D1D1D0-4838-492B-A963-4D2E17DB3494Q47949927-FCDC87CC-7F96-4828-BC00-D8608D17A2B3Q49721453-FF82751B-70FB-4D65-A5D0-70E2D9104103Q57126301-6D27A0D4-EB52-443C-8291-A69263FDF8E0Q58780116-AF714A46-0CEC-489F-A829-073B698F2BB8
P2860
A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A Generic Multi-Compartmental ...... ain Target Site Concentrations
@en
A Generic Multi-Compartmental ...... in Target Site Concentrations.
@nl
type
label
A Generic Multi-Compartmental ...... ain Target Site Concentrations
@en
A Generic Multi-Compartmental ...... in Target Site Concentrations.
@nl
prefLabel
A Generic Multi-Compartmental ...... ain Target Site Concentrations
@en
A Generic Multi-Compartmental ...... in Target Site Concentrations.
@nl
P2093
P2860
P50
P1476
A Generic Multi-Compartmental ...... ain Target Site Concentrations
@en
P2093
An Vermeulen
Claire Dahyot-Fizelier
Dymphy R Huntjens
Johannes H Proost
Meindert Danhof
Pyry A Välitalo
Robin Hartman
Sandrine Marchand
Suruchi Bakshi
Walter Krauwinkel
P2860
P304
P356
10.1007/S11095-016-2065-3
P577
2016-11-18T00:00:00Z