TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
about
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike proteinIdentification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assayCoronaviruses and the human airway: a universal system for virus-host interaction studiesAbelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion.Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.Rhesus macaque IFITM3 gene polymorphisms and SIV infection.Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza.The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.Protease inhibitors targeting coronavirus and filovirus entryInfluenza A virus encoding secreted Gaussia luciferase as useful tool to analyze viral replication and its inhibition by antiviral compounds and cellular proteins.Host cell proteases: Critical determinants of coronavirus tropism and pathogenesisInterferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses.Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropismIdentification of the Fusion Peptide-Containing Region in Betacoronavirus Spike GlycoproteinsIdentification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay.Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropismClinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry.Coronavirus entry and release in polarized epithelial cells: a review.Host Factors in Coronavirus Replication.TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.IFITM proteins inhibit entry driven by the MERS-coronavirus spike protein: evidence for cholesterol-independent mechanisms.Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.Human pulmonary 3D models for translational research.The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion.Coronavirus and influenza virus proteolytic priming takes place in tetraspanin-enriched membrane microdomainsComparative analysis of the activation of unfolded protein response by spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus HKU1.Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture.Human Coronaviruses: A Review of Virus-Host Interactions.Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses.Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains.Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells.TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
P2860
Q24339582-08203770-3329-4DD2-8985-89D3C5435B0AQ24567771-64A88A6A-E49E-41FE-A7A1-A101F45CE0B2Q28075580-794F3F3C-1E6C-4960-BBE1-B16A9F3456ADQ30276258-1A1BA5E1-AA29-4B40-A940-6B235F4C45EDQ30354466-52B1EC02-2131-44B7-9E72-1A12844919C6Q30361340-55A99CE6-F629-41F6-842C-62FE5CF7A3A1Q30365060-22CE3349-7A7F-4B7C-B6CF-43FC5A34B4EBQ30365699-DB85658A-544B-42C4-BC17-676B63007236Q30374069-1E7C83D6-9115-444E-8AEB-4526F8523457Q33602849-CE8191D3-AED8-416A-A946-EC56C6BFA996Q34461982-6F32E1C2-0FC8-4CEA-919C-E0FC627795C5Q35171172-12A5BC6B-5B97-4D8A-BD79-4B9CDBB72CE2Q35735214-98B4A645-32A6-46ED-B36D-9F564DCE5A24Q36043274-E507F98A-680C-4BDD-9929-B898C2AD4665Q36827218-9278F4B9-7EC3-458E-855C-A1A623FFB980Q36950903-2C2A9AFF-6569-4454-94F2-747E827BA1F6Q37358618-4999A542-0430-411E-A11A-18BB086FC198Q37379647-C4D519FB-CECB-42E9-99B9-604C737B1CA1Q37512759-53C42160-5DAC-4F73-A33C-A1975B69F82EQ38204957-D0FBA9CA-2279-4C18-8CF6-DF7E1736A09DQ38667715-23C4CBD2-9BE5-442F-808C-D64B17921A70Q38834744-4B93CD52-3C20-4217-9366-45A6126D9A4AQ38953321-09188926-9B84-40C8-85EC-E3CE486E5F54Q38958155-DBC2A8CB-42DF-4A21-9E4F-6C87B201D08BQ40069891-F0D7046D-5DE5-4744-81D7-78FD2B0608AFQ40101206-BDE8BCCB-6A8F-42A0-80EB-33E465D9D1F9Q40349838-721F0064-A53B-47E9-8043-235951F267FDQ41014846-A5ECE913-9C05-4BF7-99FB-2206C9475947Q41967852-0FBFA4DD-D728-4160-810F-F555987ED30FQ41975503-F3F04B6A-6B12-46EF-AEF4-2F60C711C2E9Q42051486-C52642AE-951A-4F28-B27C-841CDB5040D1Q47269172-17B03F3B-CAE8-47F1-A9EE-CBE8A3AAACFDQ50131822-A6C1FED0-FDEF-473F-8BA6-675B34A5388AQ55517889-DB42876B-F031-44A7-8486-0B7B1251E425Q57252412-CE51DE80-5B5C-4457-9378-A142764C5076
P2860
TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@en
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@nl
type
label
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@en
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@nl
prefLabel
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@en
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
TMPRSS2 activates the human co ...... in the respiratory epithelium.
@en
P2093
Adeline Heurich
Heike Hofmann-Winkler
Heike Schneider
Ilona Glowacka
Kathrin Welsch
Michael Winkler
Stefanie Gierer
Stephanie Bertram
P2860
P304
P356
10.1128/JVI.03372-12
P407
P577
2013-03-27T00:00:00Z