The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25 - Wikidata - wikimedia - TriplyDB

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25

http://www.wikidata.org/entity/Q39174910

about

Ubiquitin signaling in immune responses Regulation of antiviral innate immune signaling by stress-induced RNA granules dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects RIG-I-like receptor regulation in virus infection and immunity Viral evasion of intracellular DNA and RNA sensing Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11 The nucleolar protein GLTSCR2 is required for efficient viral replication Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response.USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31.Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness.Mechanisms and pathways of innate immune activation and regulation in health and cancer.Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms.Ubiquitination in the antiviral immune response Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis Intracellular detection of viral nucleic acids.Deubiquitylation of hepatitis B virus X protein (HBx) by ubiquitin-specific peptidase 15 (USP15) increases HBx stability and its transactivation activity.The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases.Mechanisms of RIG-I-like receptor activation and manipulation by viral pathogens.Regulation of cellular innate antiviral signaling by ubiquitin modification.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.Innate immune escape by Dengue and West Nile viruses.Post-translational Control of Intracellular Pathogen Sensing Pathways.TRIM proteins and diseases.Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity.Negative regulators of the RIG-I-like receptor signaling pathway.Antagonism of type I interferon by flaviviruses.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.The TRIMendous Role of TRIMs in Virus-Host Interactions.Finding the 'ubiquitous' threads in infection and autoimmune neuroinflammation TRIM25 in the Regulation of the Antiviral Innate Immunity Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling.Analysis of genomic copy number variation in equine recurrent airway obstruction (heaves).USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.Regulation of Cellular Antiviral Signaling by Modifications of Ubiquitin and Ubiquitin-like Molecules.Use of focused ultrasonication in activity-based profiling of deubiquitinating enzymes in tissue.

P2860

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P2860

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25

http://www.wikidata.org/entity/Q39174910

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

The ubiquitin-specific proteas ...... ing by deubiquitylating TRIM25

@en

The ubiquitin-specific proteas ...... ng by deubiquitylating TRIM25.

@nl

type

label

The ubiquitin-specific proteas ...... ing by deubiquitylating TRIM25

@en

The ubiquitin-specific proteas ...... ng by deubiquitylating TRIM25.

@nl

prefLabel

The ubiquitin-specific proteas ...... ing by deubiquitylating TRIM25

@en

The ubiquitin-specific proteas ...... ng by deubiquitylating TRIM25.

@nl

P1433

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P2860

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P932

Q39174910-DB973632-07B9-4988-89E4-828771CEB91C

P356

SCISIGNAL.2004577

P1433

Science Signaling

P1476

The ubiquitin-specific proteas ...... ing by deubiquitylating TRIM25

@en

P2093

Eva-Katharina Pauli

http://www.w3.org/2001/XMLSchema#string

Katharina F Feister

http://www.w3.org/2001/XMLSchema#string

May K Wang

http://www.w3.org/2001/XMLSchema#string

Meredith E Davis

http://www.w3.org/2001/XMLSchema#string

Michaela U Gack

http://www.w3.org/2001/XMLSchema#string

Sebastian Gableske

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Ying Kai Chan

http://www.w3.org/2001/XMLSchema#string

P2860

CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha

A ubiquitin ligase complex assembles linear polyubiquitin chains

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Activation of MDA5 requires higher-order RNA structures generated during virus infection

P304

ra3

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scholarly article

P356

10.1126/SCISIGNAL.2004577

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P433

307

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P478

7

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P577

2014-01-07T00:00:00Z

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P5875

259627718

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P698

24399297

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P921

Ubiquitin specific peptidase 15

Lys48-specific deubiquitinase activity

P932

4008495

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