Pradigastat disposition in humans: in vivo and in vitro investigations.

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Everolimus-inhibited multiple isoforms of UDP-glucuronosyltransferases (UGTs).

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P2860

Pradigastat disposition in humans: in vivo and in vitro investigations.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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name

Pradigastat disposition in humans: in vivo and in vitro investigations.

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Pradigastat disposition in humans: in vivo and in vitro investigations.

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Pradigastat disposition in humans: in vivo and in vitro investigations.

@en

Pradigastat disposition in humans: in vivo and in vitro investigations.

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Pradigastat disposition in humans: in vivo and in vitro investigations.

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Pradigastat disposition in humans: in vivo and in vitro investigations.

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P1476

Pradigastat disposition in humans: in vivo and in vitro investigations.

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P2093

Alana Upthagrove

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Angela Bretz

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Charles D Meyers

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Heidi J Einolf

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Jin Chen

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Kenneth Kulmatycki

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Lai Wang

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Lana Peng

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Melissa Lin

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Phi Tran

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P2860

Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.

Acyl glucuronide drug metabolites: toxicological and analytical implications.

Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome

Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.

Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.

Predictability of idiosyncratic drug toxicity risk for carboxylic acid-containing drugs based on the chemical stability of acyl glucuronide.

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance.

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1-13

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scholarly article

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10.1080/00498254.2016.1263405

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English

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2016-11-18T00:00:00Z

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27855567

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Pradigastat disposition in humans: in vivo and in vitro investigations.

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Pradigastat disposition in humans: in vivo and in vitro investigations.

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P1433

P1476

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P2860

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P1476

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P407

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P698