about
Conformational analysis of a glycosylated human myelin oligodendrocyte glycoprotein peptide epitope able to detect antibody response in multiple sclerosis.Structural studies on Hgr3 orphan receptor ligand prolactin-releasing peptide.Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis.A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L.New insight into the mechanism of action of the temporin antimicrobial peptides.Structure-activity relationship, conformational and biological studies of temporin L analogues.An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis.Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor.Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity.Novel α-MSH peptide analogues with broad spectrum antimicrobial activity.Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation.Design, synthesis and efficacy of novel G protein-coupled receptor kinase 2 inhibitors.De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators.Urotensin-II receptor peptide agonists.Urotensin-II receptor antagonists.Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma.New anticancer agents mimicking protein recognition motifs.Synthesis, in vitro, and in cell studies of a new series of [indoline-3,2'-thiazolidine]-based p53 modulators.Opposite modulation of cell migration by distinct subregions of urokinase connecting peptide.Characterization of a selective CaMKII peptide inhibitor.Amino Acid derivatives as new zinc binding groups for the design of selective matrix metalloproteinase inhibitors.Design, synthesis, and cytotoxic evaluation of acyl derivatives of 3-aminonaphtho[2,3-b]thiophene-4,9-dione, a quinone-based system.Identification of the spiro(oxindole-3,3'-thiazolidine)-based derivatives as potential p53 activity modulators.Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors.New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide.Spiro[(dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)]-based cytotoxic agents: structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain.Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships.Design, synthesis, and cytotoxic evaluation of a new series of 3-substituted spiro[(dihydropyrazine-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)] derivatives.An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule.The effect of d-amino acid substitution on the selectivity of temporin L towards target cells: identification of a potent anti-Candida peptide.Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.Novel cyclic biphalin analogue with improved antinociceptive properties.Synthesis and pharmacological evaluation of some 4-oxo-quinoline-2-carboxylic acid derivatives as anti-inflammatory and analgesic agents.Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives.New insight into the binding mode of peptides at urotensin-II receptor by Trp-constrained analogues of P5U and urantide.A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge.Retroinverso analogue of the antiviral octapeptide C8 inhibits feline immunodeficiency virus in serum.Unraveling the active conformation of urotensin II.Development of antiviral fusion inhibitors: short modified peptides derived from the transmembrane glycoprotein of feline immunodeficiency virus.Designed glucopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alfonso Carotenuto
@ast
Alfonso Carotenuto
@en
Alfonso Carotenuto
@es
Alfonso Carotenuto
@nl
Alfonso Carotenuto
@sl
type
label
Alfonso Carotenuto
@ast
Alfonso Carotenuto
@en
Alfonso Carotenuto
@es
Alfonso Carotenuto
@nl
Alfonso Carotenuto
@sl
prefLabel
Alfonso Carotenuto
@ast
Alfonso Carotenuto
@en
Alfonso Carotenuto
@es
Alfonso Carotenuto
@nl
Alfonso Carotenuto
@sl
P1053
C-8491-2014
P106
P21
P2798
P31
P3829
P496
0000-0001-7532-5449