ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair.
about
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivityATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.Oxidative stress in mammalian cells impinges on the cysteines redox state of human XRCC3 protein and on its cellular localization.Comparative transcriptomic analysis revealed adaptation mechanism of Phrynocephalus erythrurus, the highest altitude Lizard living in the Qinghai-Tibet Plateau.Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes.Rad51 in regulating the radiosensitivity of non-small cell lung cancer with different epidermal growth factor receptor mutation status.Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.BRCC3 mutations in myeloid neoplasms.Recombinogenic conditions influence partner choice in spontaneous mitotic recombination.Mediators of homologous DNA pairing.The essential kinase ATR: ensuring faithful duplication of a challenging genome.53BP1 fosters fidelity of homology-directed DNA repair.Trans-dichlorooxovandium (IV) complex as a novel photoinducible DNA interstrand crosslinker for cancer therapy.Discovery of mutations in homologous recombination genes in African-American women with breast cancer.FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids.ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.Redox-sensitive alteration of replisome architecture safeguards genome integrity.Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress.Coupling of Homologous Recombination and the Checkpoint by ATR.Knockdown of REV3 synergizes with ATR inhibition to promote apoptosis induced by cisplatin in lung cancer cells.Enhanced non-homologous end joining contributes toward synthetic lethality of pathological RAD51C mutants with poly (ADP-ribose) polymerase.RAD51C/XRCC3 Facilitates Mitochondrial DNA Replication and Maintains Integrity of the Mitochondrial Genome.Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3-associated signaling pathways.Loss of Rad51c accelerates tumourigenesis in sebaceous glands of Trp53-mutant mice.ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
P2860
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P2860
ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@en
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@nl
type
label
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@en
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@nl
prefLabel
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@en
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@nl
P2093
P2860
P356
P1476
ATM- and ATR-mediated phosphor ...... ckpoint activation and repair.
@en
P2093
Ganesh Nagaraju
Kumar Somyajit
Ralph Scully
Shivakumar Basavaraju
P2860
P304
P356
10.1128/MCB.01521-12
P407
P577
2013-02-25T00:00:00Z