Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.

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Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.2-Aminothiazolones as anti-HIV agents that act as gp120-CD4 inhibitors.

P2860

Q35927570-7D9E275E-AE28-4689-8E5B-D11D19229C71 Q39016799-FA7F0040-1516-4F09-8E11-F83E05909F11

P2860

Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.

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Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

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Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

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Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

@en

Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

@nl

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Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

@en

Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

@nl

P1476

Computational studies identify ...... e Phe43 cavity of HIV-1 gp120.

@en

P2093

Cristina Tintori

http://www.w3.org/2001/XMLSchema#string

José A Esté

http://www.w3.org/2001/XMLSchema#string

Manikandan Selvaraj

http://www.w3.org/2001/XMLSchema#string

Maurizio Botta

http://www.w3.org/2001/XMLSchema#string

Roger Badia

http://www.w3.org/2001/XMLSchema#string

P2860

Energetics of the HIV gp120-CD4 binding reaction

The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Structure of an unliganded simian immunodeficiency virus gp120 core

Improved protein-ligand docking using GOLD

Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.

LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters.

Compensatory mutations rescue the virus replicative capacity of VIRIP-resistant HIV-1.

P304

475-483

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P31

scholarly article

P356

10.1002/CMDC.201200584

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Bonaventura Clotet Sala

P577

2013-02-12T00:00:00Z

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P698

23404750

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Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.

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P2860

P2860

Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.

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type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698