Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
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Preventive and Therapeutic Effects of Chinese Herbal Compounds against Hepatocellular CarcinomaEvaluating the cancer therapeutic potential of cardiac glycosidesEarly downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450Pekinenin E Inhibits the Growth of Hepatocellular Carcinoma by Promoting Endoplasmic Reticulum Stress Mediated Cell Death.Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel‑7402/5‑fluorouracil cells.Activation of the mTOR signaling pathway in breast cancer MCF‑7 cells by a peptide derived from Porphyra yezoensis.Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedsideSann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways.Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.The synergistic effect of resveratrol in combination with cisplatin on apoptosis via modulating autophagy in A549 cellsProteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells.Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway.Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cellsBax-PGAM5L-Drp1 complex is required for intrinsic apoptosis executionTraditional herbal medicine: a review of potential of inhibitory hepatocellular carcinoma in basic research and clinical trial.Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells.Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy.Liang-Ge-San, a classic traditional Chinese medicine formula, protects against lipopolysaccharide-induced inflammation through cholinergic anti-inflammatory pathway.Lysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells.Development of Certain Protein Kinase Inhibitors with the Components from Traditional Chinese Medicine.Octreotide Attenuates Acute Kidney Injury after Hepatic Ischemia and Reperfusion by Enhancing Autophagy.Autophagy impacts on oxaliplatin-induced hepatocarcinoma apoptosis via the IL-17/IL-17R-JAK2/STAT3 signaling pathway.A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression.Identification of anti-tumor components from toad venom.Metabolites profiling of 10 bufadienolides in human liver microsomes and their cytotoxicity variation in HepG2 cell.SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.Analysis of proliferation and apoptotic induction by 20 steroid glycosides in 143B osteosarcoma cells in vitro.Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway.Systemic delivery of the anticancer agent arenobufagin using polymeric nanomicelles.Elaborating the role of natural products-induced autophagy in cancer treatment: achievements and artifacts in the state of the art.The role of autophagy in hepatocellular carcinoma: friend or foe.Two preclinical tests to evaluate anticancer activity and to help validate drug candidates for clinical trials.Arenobufagin activates p53 to trigger esophageal squamous cell carcinoma cell apoptosis in vitro and in vivo.Expression of the β3 subunit of Na+/K+-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway.Identification of Bufadienolides from the Boreal Toad, Anaxyrus boreas, Active Against a Fungal Pathogen.DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathway.Effect of arenobufagin on human pancreatic carcinoma cells.Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling.Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine.Arenobufagin Induces Apoptotic Cell Death in Human Non-Small-Cell Lung Cancer Cells via the Noxa-Related Pathway.
P2860
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P2860
Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Arenobufagin, a natural bufadi ...... tion of PI3K/Akt/mTOR pathway.
@en
Arenobufagin, a natural bufadi ...... tion of PI3K/Akt/mTOR pathway.
@nl
type
label
Arenobufagin, a natural bufadi ...... tion of PI3K/Akt/mTOR pathway.
@en
Arenobufagin, a natural bufadi ...... tion of PI3K/Akt/mTOR pathway.
@nl
prefLabel
Arenobufagin, a natural bufadi ...... tion of PI3K/Akt/mTOR pathway.
@en
Arenobufagin, a natural bufadi ...... tion of PI3K/Akt/mTOR pathway.
@nl
P2093
P2860
P356
P1433
P1476
Arenobufagin, a natural bufadi ...... ition of PI3K/Akt/mTOR pathway
@en
P2093
Dong-Mei Zhang
Hai-Yan Tian
Hiroshi Kurihara
Hui-Hui Cao
Jing-Xuan Pan
Jun-Shan Liu
Li-Juan Deng
Min-Feng Chen
Wen-Cai Ye
P2860
P304
P356
10.1093/CARCIN/BGT060
P407
P577
2013-02-07T00:00:00Z