In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
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Exploring miRNA-Associated Signatures with Diagnostic Relevance in Glioblastoma Multiforme and Breast Cancer PatientsMicroRNA expression signatures determine prognosis and survival in glioblastoma multiforme--a systematic overview.A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas.Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review).Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.CPSF30 at the Interface of Alternative Polyadenylation and Cellular Signaling in PlantsAlternative polyadenylation can regulate post-translational membrane localization.Personalized treatment strategies in glioblastoma: MGMT promoter methylation status.Inhibiting MicroRNA-503 and MicroRNA-181d with Losartan Ameliorates Diabetic Nephropathy in KKAy Mice.Double-labelling immunohistochemistry for MGMT and a "cocktail" of non-tumourous elements is a reliable, quick and easy technique for inferring methylation status in glioblastomas and other primary brain tumours.Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment.MGMT testing--the challenges for biomarker-based glioma treatment.Alternative polyadenylation: less than meets the eye?MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT.miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma.Cleavage and polyadenylation: Ending the message expands gene regulation.RNA processing as an alternative route to attack glioblastoma.Biomarkers and therapeutic advances in glioblastoma multiforme.Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomas.The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma.Prognosis of glioblastoma with faint MGMT methylation-specific PCR product.Repair gene O6 -methylguanine-DNA methyltransferase is controlled by SP1 and up-regulated by glucocorticoids, but not by temozolomide and radiation.Extensive miRNA expression analysis in craniopharyngiomas.Mesenchymal stem cells cancel azoxymethane-induced tumor initiation.microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells.Alternative polyadenylation factors link cell cycle to migration
P2860
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P2860
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@en
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@nl
type
label
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@en
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@nl
prefLabel
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@en
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@nl
P2093
P2860
P1476
In human glioblastomas transcr ...... t mechanism of MGMT silencing.
@en
P2093
Elisabeth Limbeck
Friedrich W Kreth
Kai Hoefig
Ludwig C Hinske
Niklas Thon
Rupert Egensperger
Simone Kreth
Stefanie V Schütz
P2860
P2888
P304
P356
10.1007/S00401-013-1081-1
P577
2013-01-23T00:00:00Z