Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.
about
Getting the genome in shape: the formation of loops, domains and compartmentsFOXO3: A Major Gene for Human Longevity--A Mini-ReviewInterplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogasterDAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegansLagging-strand replication shapes the mutational landscape of the genomeTopology of mammalian developmental enhancers and their regulatory landscapes.A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genesA genome-wide RNAi screen identifies FOXO4 as a metastasis-suppressor through counteracting PI3K/AKT signal pathway in prostate cancer.Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy.A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis.Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells.FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans.FoxO3 suppresses Myc-driven lymphomagenesis.Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression.Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.Variation of lifespan in multiple strains, and effects of dietary restriction and BmFoxO on lifespan in silkworm, Bombyx mori.Antagonism between FOXO and MYC Regulates Cellular Powerhouse.The 3D genome in transcriptional regulation and pluripotencyEukaryotic enhancers: common features, regulation, and participation in diseases.Architectural hallmarks of the pluripotent genome.Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promotersOverexpression of LINE-1 Retrotransposons in Autism Brain.FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 expression.FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis.FOXO3A regulatory polymorphism and susceptibility to severe malaria in Gabonese children.5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR.Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancerMyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation.Enhancers reside in a unique epigenetic environment during early zebrafish development.FOXO1 regulates expression of a microRNA cluster on X chromosome.Oncogenic regulation of tumor metabolic reprogramming.Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway.FOXO3 and related transcription factors in development, aging, and exceptional longevity.Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers.Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures.Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover.
P2860
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P2860
Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@en
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@nl
type
label
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@en
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@nl
prefLabel
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@en
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@nl
P2093
P2860
P50
P356
P1476
Genome-wide analysis of FOXO3 ...... h RNA polymerase II profiling.
@en
P2093
Astrid Eijkelenboom
Boudewijn M T Burgering
Edwin Cuppen
Lydia M Smits
Miranda H van Triest
Paulien E Polderman
P2860
P356
10.1038/MSB.2012.74
P577
2013-01-01T00:00:00Z