Targeted, high-depth, next-generation sequencing of cancer genes in formalin-fixed, paraffin-embedded and fine-needle aspiration tumor specimens. - Wikidata - wikimedia - TriplyDB

Targeted, high-depth, next-generation sequencing of cancer genes in formalin-fixed, paraffin-embedded and fine-needle aspiration tumor specimens.

Targeted, high-depth, next-generation sequencing of cancer genes in formalin-fixed, paraffin-embedded and fine-needle aspiration tumor specimens.

http://www.wikidata.org/entity/Q39210091

about

Is there still a role for thyroid scintigraphy in the workup of a thyroid nodule in the era of fine needle aspiration cytology and molecular testing?Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies Navigating the rapids: the development of regulated next-generation sequencing-based clinical trial assays and companion diagnostics Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective Validation of biomarkers to predict response to immunotherapy in cancer: Volume I - pre-analytical and analytical validation Clinical Application of Targeted Next Generation Sequencing for Colorectal Cancers Next generation MUT-MAP, a high-sensitivity high-throughput microfluidics chip-based mutation analysis panel Novel insight into mutational landscape of head and neck squamous cell carcinoma Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population.An NGS Workflow Blueprint for DNA Sequencing Data and Its Application in Individualized Molecular Oncology.Multi-marker Solid Tumor Panels Using Next-generation Sequencing to Direct Molecularly Targeted Therapies.'Druggable' alterations detected by Ion Torrent in metastatic colorectal cancer patients PIK3CA and TP53 gene mutations in human breast cancer tumors frequently detected by ion torrent DNA sequencing.Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups.Systematic comparison of two whole-genome amplification methods for targeted next-generation sequencing using frozen and FFPE normal and cancer tissues.Distribution of somatic mutations of cancer-related genes according to microsatellite instability status in Korean gastric cancer.Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications.Reporting tumor molecular heterogeneity in histopathological diagnosis.Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail Evaluation of an integrated clinical workflow for targeted next-generation sequencing of low-quality tumor DNA using a 51-gene enrichment panel.Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues.Emerging understanding of multiscale tumor heterogeneity Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium Retrospective review using targeted deep sequencing reveals mutational differences between gastroesophageal junction and gastric carcinomas.Predictive efficacy of low burden EGFR mutation detected by next-generation sequencing on response to EGFR tyrosine kinase inhibitors in non-small-cell lung carcinoma Next-generation sequencing of lung cancer EGFR exons 18-21 allows effective molecular diagnosis of small routine samples (cytology and biopsy).Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencing.Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy.Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors.Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.Evaluation of two highly-multiplexed custom panels for massively parallel semiconductor sequencing on paraffin DNA Phasing amplicon sequencing on Illumina Miseq for robust environmental microbial community analysis.A new method to prevent carry-over contaminations in two-step PCR NGS library preparations Factors affecting the success of next-generation sequencing in cytology specimens.Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers.Identification of Genetic Mutations in Human Lung Cancer by Targeted Sequencing.Whole exome sequencing (WES) on formalin-fixed, paraffin-embedded (FFPE) tumor tissue in gastrointestinal stromal tumors (GIST).

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Targeted, high-depth, next-generation sequencing of cancer genes in formalin-fixed, paraffin-embedded and fine-needle aspiration tumor specimens.

http://www.wikidata.org/entity/Q39210091

description

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J.JMOLDX.2012.11.006

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The Journal of Molecular Diagnostics

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Adam C Marko

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