Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity.
about
A novel 3D label-free monitoring system of hES-derived cardiomyocyte clusters: a step forward to in vitro cardiotoxicity testingUse of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways.Examining the protective role of ErbB2 modulation in human-induced pluripotent stem cell-derived cardiomyocytes.Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicityPhysiological, pharmacological and toxicological considerations of drug-induced structural cardiac injuryStatic image analysis as new approach for the characterization of tumor cell lysate used in dendritic cell vaccine preparationA phenotypic in vitro model for the main determinants of human whole heart function.Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells.Stem cells and stem cell-derived tissues and their use in safety assessment.High-content analysis in toxicology: screening substances for human toxicity potential, elucidating subcellular mechanisms and in vivo use as translational safety biomarkers.Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line.Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues.Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment.Profiling of Nutrient Transporter Expression in Human Stem Cell-Derived Cardiomyocytes Exposed to Tyrosine Kinase Inhibitor Anticancer Drugs Using RBD Ligands.An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility.Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays.
P2860
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P2860
Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@en
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@nl
type
label
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@en
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@nl
prefLabel
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@en
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@nl
P2093
P2860
P356
P1476
Phenotypic profiling of struct ...... ltiple mechanisms of toxicity.
@en
P2093
Amy Pointon
James E Sidaway
Michael J Cross
Najah Abi-Gerges
P2860
P304
P356
10.1093/TOXSCI/KFT005
P577
2013-01-12T00:00:00Z