A complex network of factors with overlapping affinities represses splicing through intronic elements. - Wikidata - wikimedia - TriplyDB

A complex network of factors with overlapping affinities represses splicing through intronic elements.

A complex network of factors with overlapping affinities represses splicing through intronic elements.

http://www.wikidata.org/entity/Q39225814

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mRNA trans-splicing in gene therapy for genetic diseases Engineering RNA-binding proteins with diverse activities Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process Alu elements: at the crossroads between disease and evolution In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors Context-dependent control of alternative splicing by RNA-binding proteins A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy Evolution at protein ends: major contribution of alternative transcription initiation and termination to the transcriptome and proteome diversity in mammals.Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex.RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform.Mechanisms and Regulation of Alternative Pre-mRNA Splicing Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate.Transcriptome-wide modulation of splicing by the exon junction complex.Systematical identification of splicing regulatory cis-elements and cognate trans-factors Efficient backsplicing produces translatable circular mRNAs.Alternative RNA splicing and cancer Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors.TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor.Engineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism.Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction Treatment of type 1 myotonic dystrophy by engineering site-specific RNA endonucleases that target (CUG)(n) repeats.Mammalian synthetic biology for studying the cell.Epigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analyses Role of pseudoexons and pseudointrons in human cancer.A day in the life of the spliceosome RBM20, a potential target for treatment of cardiomyopathy via titin isoform switching.The determinants of alternative RNA splicing in human cells.TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways A comprehensive survey of non-canonical splice sites in the human transcriptome.SR Proteins: Binders, Regulators, and Connectors of RNA.Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing.Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation Splicing defects caused by exonic mutations in PKD1 as a new mechanism of pathogenesis in autosomal dominant polycystic kidney disease.Transcriptome-Wide Identification of RNA Targets of Arabidopsis SERINE/ARGININE-RICH45 Uncovers the Unexpected Roles of This RNA Binding Protein in RNA Processing.Activation of a cryptic 5' splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene.RIT2 Polymorphisms: Is There a Differential Association?Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells.

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A complex network of factors with overlapping affinities represses splicing through intronic elements.

http://www.wikidata.org/entity/Q39225814

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年论文

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name

A complex network of factors w ...... ing through intronic elements.

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A complex network of factors w ...... ing through intronic elements.

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type

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A complex network of factors w ...... ing through intronic elements.

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A complex network of factors w ...... ing through intronic elements.

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A complex network of factors w ...... ing through intronic elements.

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A complex network of factors w ...... ing through intronic elements.

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Nature Structural & Molecular Biology

P1476

A complex network of factors w ...... ing through intronic elements.

@en

P2093

Alex Robertson

http://www.w3.org/2001/XMLSchema#string

Christopher B Burge

http://www.w3.org/2001/XMLSchema#string

Jianming Zhang

http://www.w3.org/2001/XMLSchema#string

Kai Li

http://www.w3.org/2001/XMLSchema#string

Meng Ma

http://www.w3.org/2001/XMLSchema#string

Rajarshi Choudhury

http://www.w3.org/2001/XMLSchema#string

P2860

A 3' exonuclease that specifically interacts with the 3' end of histone mRNA

Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing.

hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells

Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes

Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins

Splicing regulation: from a parts list of regulatory elements to an integrated splicing code

The RasGAP-associated endoribonuclease G3BP assembles stress granules

General and specific functions of exonic splicing silencers in splicing control

p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation.

HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats

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36-45

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10.1038/NSMB.2459

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1

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20

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233930400

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1019375344

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23241926

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3537874

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