about
A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipidMechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blockerFour basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels.Conditional knockout of TMEM16A/anoctamin1 abolishes the calcium-activated chloride current in mouse vomeronasal sensory neurons.Molecular and functional significance of Ca(2+)-activated Cl(-) channels in pulmonary arterial smooth muscle.Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex.New selective inhibitors of calcium-activated chloride channels - T16A(inh) -A01, CaCC(inh) -A01 and MONNA - what do they inhibit?A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2.Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal.Inhibition of calcium-activated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells.Influence of intracellular Ca2+ and alternative splicing on the pharmacological profile of ANO1 channels.ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter.Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels.Study of permeation and blocker binding in TMEM16A calcium-activated chloride channels.Pharmacological properties of native CaCCs and TMEM16A.Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.A Calcium-Dependent Chloride Current Increases Repetitive Firing in Mouse Sympathetic Neurons.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Pharmacological characterization of TMEM16A currents
@en
Pharmacological characterization of TMEM16A currents.
@nl
type
label
Pharmacological characterization of TMEM16A currents
@en
Pharmacological characterization of TMEM16A currents.
@nl
prefLabel
Pharmacological characterization of TMEM16A currents
@en
Pharmacological characterization of TMEM16A currents.
@nl
P2093
P2860
P50
P356
P1433
P1476
Pharmacological characterization of TMEM16A currents
@en
P2093
Eamonn Bradley
Noel G McHale
Stephen Fedigan
Timothy Webb
P2860
P304
P356
10.4161/CHAN.28065
P577
2014-01-01T00:00:00Z