Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. - Wikidata - wikimedia - TriplyDB

Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.

Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.

http://www.wikidata.org/entity/Q39237609

about

Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growth La FAM fatale: USP9X in development and disease Systematic approaches to identify E3 ligase substrates Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase A proteomic perspective of inbuilt viral protein regulation: pUL46 tegument protein is targeted for degradation by ICP0 during herpes simplex virus type 1 infection.USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7 Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinoma Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover p53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling.New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1 Reduced ubiquitin-specific protease 9X expression induced by RNA interference inhibits the bioactivity of hepatocellular carcinoma cells De Novo Loss-of-Function Mutations in USP9X Cause a Female-Specific Recognizable Syndrome with Developmental Delay and Congenital Malformations Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cells The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti-apoptotic activities in breast cancer cells.The deubiquitinating enzyme DUBAI stabilizes DIAP1 to suppress Drosophila apoptosis.USP9X destabilizes pVHL and promotes cell proliferation.Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Specificity and regulation of the endoplasmic reticulum-associated degradation machinery.Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.HECT-type E3 ubiquitin ligases in nerve cell development and synapse physiology.E3 ubiquitin ligases in regulating stress fiber, lamellipodium, and focal adhesion dynamics.PP2A as a master regulator of the cell cycle.Deubiquitylating enzyme, USP9X, regulates proliferation of cells of head and neck cancer lines.Regulation of pluripotency and differentiation by deubiquitinating enzymes.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.Aberrant Phosphorylation of SMAD4 Thr277-Mediated USP9x-SMAD4 Interaction by Free Fatty Acids Promotes Breast Cancer Metastasis.The role of deubiquitinases in breast cancer.Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.Bone morphogenetic proteins, breast cancer, and bone metastases: striking the right balance.A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers.Identification of UT-A1- and AQP2-interacting proteins in rat inner medullary collecting duct.Suppression of the Smurf1 Expression Inhibits Tumor Progression in Gliomas.Decreased expression of USP9X is associated with poor prognosis in Chinese pancreatic ductal adenocarcinoma patients.Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line

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P2860

Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.

http://www.wikidata.org/entity/Q39237609

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@en

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@nl

type

label

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@en

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@nl

prefLabel

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@en

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@nl

P1433

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P1476

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P2093

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P2860

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P932

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P356

JBC.M112.430066

P1433

Journal of Biological Chemistry

P1476

Deubiquitinase FAM/USP9X inter ...... ty-dependent self-degradation.

@en

P2093

Christopher Wilson

http://www.w3.org/2001/XMLSchema#string

Elizabeth McWhinnie

http://www.w3.org/2001/XMLSchema#string

Eva Bric-Furlong

http://www.w3.org/2001/XMLSchema#string

Feng Cong

http://www.w3.org/2001/XMLSchema#string

Jing Zhang

http://www.w3.org/2001/XMLSchema#string

Marc W Kirschner

http://www.w3.org/2001/XMLSchema#string

Markus Schirle

http://www.w3.org/2001/XMLSchema#string

Monika Avello

http://www.w3.org/2001/XMLSchema#string

Robin Nathans

http://www.w3.org/2001/XMLSchema#string

Shih-Min A Huang

http://www.w3.org/2001/XMLSchema#string

P2860

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

Image-based genome-wide siRNA screen identifies selective autophagy factors

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.

The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization

Defining the human deubiquitinating enzyme interaction landscape

P304

2976-2985

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scholarly article

P356

10.1074/JBC.M112.430066

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P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

288

http://www.w3.org/2001/XMLSchema#string

P577

2012-11-26T00:00:00Z

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P698

23184937

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P932

3561522

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