BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery.
about
The sweet trap in tumors: aerobic glycolysis and potential targets for therapyEnergy metabolism in neuroblastoma and Wilms tumorSurvivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasionMitochondria and FOXO3: breath or dieErk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.Bioenergetic analysis of ovarian cancer cell lines: profiling of histological subtypes and identification of a mitochondria-defective cell line.Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysisHormone Resistance in Two MCF-7 Breast Cancer Cell Lines is Associated with Reduced mTOR Signaling, Decreased Glycolysis, and Increased Sensitivity to Cytotoxic Drugs.The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of SurvivinRegulators of mitochondrial dynamics in cancer.Reversal of multidrug resistance in gastric cancer cells by CDX2 downregulationITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cells.Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma.The role of dynamin-related protein 1 in cancer growth: a promising therapeutic target?Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming.The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastomaBIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma.Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration.The MYCN Protein in Health and Disease.Mitochondrial dynamics and cancer.Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer.The regulation of tumor cell physiology by mitochondrial dynamics.The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulatorSelective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate.Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and NoxaThe intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation.Mitochondrial survivin - an Achilles' heel in cancer chemoresistance.FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3.Correlation between E-cadherin interactions, survivin expression, and apoptosis in MDCK and ts-Src MDCK cell culture models.Cancer, Oxidative Stress, and Metastasis.Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin.Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin.Cell death-based treatment of neuroblastoma.Therapeutic potential of targeting glucose metabolism in glioma stem cells.Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery.Mitochondrial Dynamics in Basal and Stressful Conditions.Dynamin-Related Protein 1 at the Crossroads of Cancer.
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P2860
BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
BIRC5/Survivin enhances aerobi ...... rial fusion/fission machinery.
@en
BIRC5/Survivin enhances aerobi ...... rial fusion/fission machinery.
@nl
type
label
BIRC5/Survivin enhances aerobi ...... rial fusion/fission machinery.
@en
BIRC5/Survivin enhances aerobi ...... rial fusion/fission machinery.
@nl
prefLabel
BIRC5/Survivin enhances aerobi ...... rial fusion/fission machinery.
@en
BIRC5/Survivin enhances aerobi ...... rial fusion/fission machinery.
@nl
P2860
P356
P1433
P1476
BIRC5/Survivin enhances aerobi ...... drial fusion/fission machinery
@en
P2093
A V Kuznetsov
P2860
P2888
P304
P356
10.1038/ONC.2012.500
P407
P577
2012-11-12T00:00:00Z