Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
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Wnt Signaling in Cancer Stem Cell BiologyTargeting Wnt/β-catenin pathway in hepatocellular carcinoma treatmentTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28Targeting the Wnt signaling pathways in pulmonary arterial hypertensionTankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitroPoly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model.Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling.FH535 Suppresses Osteosarcoma Growth In Vitro and Inhibits Wnt Signaling through TankyrasesThe oncogenic potential of human cytomegalovirus and breast cancer.Evidence for tankyrases as antineoplastic targets in lung cancer.Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.ERCC1 and telomere status in breast tumours treated with neoadjuvant chemotherapy and their association with patient prognosisThe Importance of the Canonical Wnt Signaling Pathway in the Porcine Endometrial Stromal Stem/Progenitor Cells: Implications for RegenerationClinical implications of Girdin and PI3K protein expression in breast cancer.The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway.Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers.New insights into the regulation of Axin function in canonical Wnt signaling pathway.Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.Tankyrases: structure, function and therapeutic implications in cancer.WNT signaling: an emerging mediator of cancer cell metabolism?The roles of AXIN2 in tumorigenesis and epigenetic regulation.Targeting the WNT Signaling Pathway in Cancer Therapeutics.Breast cancer stem cells: are we ready to go from bench to bedside?MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells.A novel microRNA located in the TrkC gene regulates the Wnt signaling pathway and is differentially expressed in colorectal cancer specimens.Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway.Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase--A Potential Strategy for Suppression of the Wnt Pathway.Tankyrase-mediated β-catenin activity regulates vasopressin-induced AQP2 expression in kidney collecting duct mpkCCDc14 cells.Arhgef7 promotes activation of the Hippo pathway core kinase LatsXAV939, a small molecular inhibitor, provides neuroprotective effects on oligodentrocytes.Endometrial Carcinoma: Specific Targeted Pathways.Wnt signaling in triple-negative breast cancer.AZ1366: An Inhibitor of Tankyrase and the Canonical Wnt Pathway that Limits the Persistence of Non-Small Cell Lung Cancer Cells Following EGFR Inhibition.Vitamin D receptor is a novel transcriptional regulator for Axin1.Design and Discovery of 2-Arylquinazolin-4-ones as Potent and Selective Inhibitors of Tankyrases.An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function.
P2860
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P2860
Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@en
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@nl
type
label
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@en
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@nl
prefLabel
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@en
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@nl
P2093
P2860
P1433
P1476
Inhibition of tankyrases induc ...... alling in breast cancer cells.
@en
P2093
Liliana Attisano
Renyue Bao
Siyuan Song
Tania Christova
Xiaojun Yan
P2860
P304
P356
10.1371/JOURNAL.PONE.0048670
P407
P577
2012-11-07T00:00:00Z