A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells
about
KLF8 knockdown suppresses proliferation and invasion in human osteosarcoma cells.Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencingTdIF1 recognizes a specific DNA sequence through its Helix-Turn-Helix and AT-hook motifs to regulate gene transcription.Functional genomics screening utilizing mutant mouse embryonic stem cells identifies novel radiation-response genes.Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancerERK2 phosphorylates Krüppel-like factor 8 protein at serine 48 to maintain its stability.Krüppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146a.Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis.KLF8 and FAK cooperatively enrich the active MMP14 on the cell surface required for the metastatic progression of breast cancerIdentification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasisTranscriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.Effects and mechanism of flavonoids from Astragalus complanatus on breast cancer growth.Cerium Oxide Nanoparticles Sensitize Pancreatic Cancer to Radiation Therapy through Oxidative Activation of the JNK Apoptotic Pathway
P2860
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P2860
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells
@en
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells.
@nl
type
label
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells
@en
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells.
@nl
prefLabel
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells
@en
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells.
@nl
P2093
P2860
P356
P1476
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells
@en
P2093
Debarati Mukherjee
Melissa S Wason
Satadru Lahiri
Tianshu Li
P2860
P304
43720-43729
P356
10.1074/JBC.M112.418053
P407
P577
2012-10-26T00:00:00Z