A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity.
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Yeast prions: structure, biology, and prion-handling systemsOverexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis.Normal levels of the antiprion proteins Btn2 and Cur1 cure most newly formed [URE3] prion variantsYeast prions: proteins templating conformation and an anti-prion systemPrions are affected by evolution at two levelsNon-targeted identification of prions and amyloid-forming proteins from yeast and mammalian cells.Effects of mutations and deletions in the human optineurin gene.Harnessing the power of yeast to unravel the molecular basis of neurodegeneration.Protein aggregation in amyotrophic lateral sclerosis.Advances in cellular models to explore the pathophysiology of amyotrophic lateral sclerosis.Dynamic droplets: the role of cytoplasmic inclusions in stress, function, and disease.Interaction between optineurin and Rab1a regulates autophagosome formation in neuroblastoma cells.Stress granules at the intersection of autophagy and ALS.Yeast and Fungal Prions.Major review: Molecular genetics of primary open-angle glaucoma.Protein aggregates are associated with replicative aging without compromising protein quality control.Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug targetYeast models for amyloid disease.Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma.Hsp104 disaggregase at normal levels cures many [PSI+] prion variants in a process promoted by Sti1p, Hsp90, and Sis1p.Nonsense-mediated mRNA decay factors cure most [PSI+] prion variants.Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma.ALS Yeast Models—Past Success Stories and New Opportunities
P2860
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P2860
A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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name
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@en
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@nl
type
label
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@en
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@nl
prefLabel
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@en
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@nl
P2093
P2860
P356
P1476
A yeast model of optineurin pr ...... ciated with cellular toxicity.
@en
P2093
Dmitry Kryndushkin
Frank Shewmaker
Gudrun Ihrke
Tetsade C Piermartiri
P2860
P304
P356
10.1111/MMI.12075
P407
P577
2012-11-09T00:00:00Z