Notch signaling regulates PD-1 expression during CD8(+) T-cell activation. - Wikidata - wikimedia - TriplyDB

Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

http://www.wikidata.org/entity/Q39258612

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The immunological synapse: the gateway to the HIV reservoir The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation Adjunct Strategies for Tuberculosis Vaccines: Modulating Key Immune Cell Regulatory Mechanisms to Potentiate Vaccination Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression.Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses.Myeloid-derived suppressor cells impair alveolar macrophages through PD-1 receptor ligation during Pneumocystis pneumonia.Notch Signaling Pathway Was Involved in Regulating Programmed Cell Death 1 Expression during Sepsis-Induced Immunosuppression Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4+ recent thymic emigrants.Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs.Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family.Corneal Allograft Rejection: Immunopathogenesis to Therapeutics.The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.Genetic and Epigenetic Regulation of PD-1 Expression Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway.Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses.A genomic variant in IRF9 is associated with serum cytokine levels in pig.Prolonged PD1 Expression on Neonatal Vδ2 Lymphocytes Dampens Proinflammatory Responses: Role of Epigenetic Regulation.PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade.Investigational PD-1 inhibitors in HL and NHL and biomarkers for predictors of response and outcome.Immune Checkpoint Blockade in Breast Cancer Therapy.Regulation of CD8+ T Cells and Antitumor Immunity by Notch Signaling.BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment.Notch Signaling in Macrophages in the Context of Cancer Immunity.Cancer Cells Exploit Notch Signaling to Redefine a Supportive Cytokine Milieu

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Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

http://www.wikidata.org/entity/Q39258612

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Notch signaling regulates PD-1 expression during CD8

@nl

Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

@en

type

label

Notch signaling regulates PD-1 expression during CD8

@nl

Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

@en

prefLabel

Notch signaling regulates PD-1 expression during CD8

@nl

Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

@en

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Immunology & Cell Biology

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Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

@en

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Jean-François Daudelin

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Mélissa Mathieu

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Natacha Cotta-Grand

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Nathalie Labrecque

http://www.w3.org/2001/XMLSchema#string

Paméla Thébault

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P2860

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor

Direct inhibition of the NOTCH transcription factor complex

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Restoring function in exhausted CD8 T cells during chronic viral infection

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82-88

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scholarly article

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10.1038/ICB.2012.53

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1

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91

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23070399

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