Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.
about
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALMStructural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsBiallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunctionSorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processingLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseβ-Amyloid: the key peptide in the pathogenesis of Alzheimer's diseaseThe role of APP and BACE1 trafficking in APP processing and amyloid-β generationTrafficking regulation of proteins in Alzheimer's diseaseCellular mechanisms of γ-secretase substrate selection, processing and toxicityPhosphoinositides in the mammalian endo-lysosomal networkConcepts of papillomavirus entry into host cellsPhox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPasesStructural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Biogenesis of endosome-derived transport carriers.SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cellsProteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing.Pyroglutamate-amyloid-β and glutaminyl cyclase are colocalized with amyloid-β in secretory vesicles and undergo activity-dependent, regulated secretion.MEGF10 functions as a receptor for the uptake of amyloid-β.Altering APP proteolysis: increasing sAPPalpha production by targeting dimerization of the APP ectodomainCargo recognition in clathrin-mediated endocytosisDysregulation of protein trafficking in neurodegeneration.Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channelsHIV-1 Tat interacts with and regulates the localization and processing of amyloid precursor protein.Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity.Physiology and pathology of endosome-to-Golgi retrograde sorting.Sorting nexin 17 regulates ApoER2 recycling and reelin signalingHuman papillomavirus L2 facilitates viral escape from late endosomes via sorting nexin 17.SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathwaysA sorting nexin 17-binding domain within the LRP1 cytoplasmic tail mediates receptor recycling through the basolateral sorting endosome.Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complexSorting nexin-4 regulates β-amyloid production by modulating β-site-activating cleavage enzyme-1.Amyloid-beta immunotherapy: the hope for Alzheimer disease?Membrane rafts in Alzheimer's disease beta-amyloid production.Amyloid precursor protein processing and Alzheimer's diseaseIntracellular trafficking of the β-secretase and processing of amyloid precursor protein.The role of lipoprotein receptors on the physiological function of APP.Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.Sorting nexins provide diversity for retromer-dependent trafficking events.miR-98-5p Acts as a Target for Alzheimer's Disease by Regulating Aβ Production Through Modulating SNX6 Expression.Disabled-2: A modular scaffold protein with multifaceted functions in signaling.
P2860
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P2860
Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Adaptor protein sorting nexin ...... essing in the early endosomes.
@en
Adaptor protein sorting nexin ...... essing in the early endosomes.
@nl
type
label
Adaptor protein sorting nexin ...... essing in the early endosomes.
@en
Adaptor protein sorting nexin ...... essing in the early endosomes.
@nl
prefLabel
Adaptor protein sorting nexin ...... essing in the early endosomes.
@en
Adaptor protein sorting nexin ...... essing in the early endosomes.
@nl
P2093
P2860
P356
P1476
Adaptor protein sorting nexin ...... essing in the early endosomes.
@en
P2093
Amy Caruano-Yzermans
Claudio Retamal
Jiyeon Lee
Jung-Eun Shin
Loreto Cuitiño
Maria-Paz Marzolo
Peter van Kerkhof
P2860
P304
11501-11508
P356
10.1074/JBC.M800642200
P407
P577
2008-02-13T00:00:00Z