Kidney proximal tubular epithelial-specific overexpression of netrin-1 suppresses inflammation and albuminuria through suppression of COX-2-mediated PGE2 production in streptozotocin-induced diabetic mice.
about
Guidance cue netrin-1 and the regulation of inflammation in acute and chronic kidney diseaseRole of COX-2/mPGES-1/prostaglandin E2 cascade in kidney injury.Deletion of UNC5B in Kidney Epithelium Exacerbates Diabetic Nephropathy in MiceSteap4 attenuates high glucose and S100B-induced effects in mesangial cells.Netrin-1 attenuates the progression of renal dysfunction by blocking endothelial-to-mesenchymal transition in the 5/6 nephrectomy rat model.Proximal tubule-specific overexpression of netrin-1 suppresses acute kidney injury-induced interstitial fibrosis and glomerulosclerosis through suppression of IL-6/STAT3 signalingNetrin-1-treated macrophages protect the kidney against ischemia-reperfusion injury and suppress inflammation by inducing M2 polarization.Netrin-1 regulates colon-kidney cross talk through suppression of IL-6 function in a mouse model of DSS-colitis.Protective role for netrin-1 during diabetic nephropathy.Netrin-1, a urinary proximal tubular injury marker, is elevated early in the time course of human diabetes.Tubular injury marker netrin-1 is elevated early in experimental diabetesChronic kidney disease: targeting prostaglandin E2 receptors.Prostaglandin E2 increases proximal tubule fluid reabsorption, and modulates cultured proximal tubule cell responses via EP1 and EP4 receptors.Netrin-1 promoted pancreatic cancer cell proliferation by upregulation of Mdm2.Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms.The anti-inflammatory and anti-glycative effects of rosmarinic acid in the livers of type 1 diabetic mice.Chronic administration of EP4-selective agonist exacerbates albuminuria and fibrosis of the kidney in streptozotocin-induced diabetic mice through IL-6.Neutrophils Infiltrate the Spinal Cord Parenchyma of Rats with Experimental Diabetic NeuropathyNetrin-1 is a novel regulator of vascular endothelial function in diabetes.Lentiviral-Mediated Netrin-1 Overexpression Improves Motor and Sensory Functions in SCT Rats Associated with SYP and GAP-43 Expressions.Swerving away from diabetic nephropathy by means of divine guidance.Acute Kidney Injury and Progression of Diabetic Kidney Disease.Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells.Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptor.Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications
P2860
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P2860
Kidney proximal tubular epithelial-specific overexpression of netrin-1 suppresses inflammation and albuminuria through suppression of COX-2-mediated PGE2 production in streptozotocin-induced diabetic mice.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@en
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@nl
type
label
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@en
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@nl
prefLabel
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@en
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@nl
P2093
P2860
P1476
Kidney proximal tubular epithe ...... zotocin-induced diabetic mice.
@en
P2093
Calpurnia Jayakumar
Ganesan Ramesh
Punithavathi V Ranganathan
Riyaz Mohamed
P2860
P304
P356
10.1016/J.AJPATH.2012.08.014
P407
P577
2012-10-02T00:00:00Z