Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells.
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Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus- and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cellsHuman T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-kappaB activation.PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell lineTLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathwaysRearranged NF-kappa B2 gene in an adult T-cell leukemia cell line.Mechanisms of nanoparticle-mediated siRNA transfection by melittin-derived peptides.Combination of 9-aminoacridine with Campath-1H provides effective therapy for a murine model of adult T-cell leukemiaMiR-30a targets IL-1α and regulates islet functions as an inflammation buffer and response factor.A-kinase-interacting protein 1 (AKIP1) acts as a molecular determinant of PKA in NF-kappaB signaling.Pneumocystis activates human alveolar macrophage NF-kappaB signaling through mannose receptorsCopy-number variation of cancer-gene orthologs is sufficient to induce cancer-like symptoms in Saccharomyces cerevisiae.7-ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NFκB but independently of reactive oxygen species formationInhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I-associated neurologic disease.Differential drug resistance acquisition to doxorubicin and paclitaxel in breast cancer cells.Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/gammac(null) mice: suppression by an inhibitor against NF-kappaBArginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia.Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-κB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisThe TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.NF-kappaB inhibits gammaherpesvirus lytic replicationSignal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.NF-kappaB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop.Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.The synergistic repressive effect of NF-κB and JNK inhibitor on the clonogenic capacity of Jurkat leukemia cells.Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells.Emodin and DHA potently increase arsenic trioxide interferon-alpha-induced cell death of HTLV-I-transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphomaAdult T cell leukemia lymphoma.Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade.Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAsTax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cellsProapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kappaB pathway.Pathophysiological changes induced by Pseudomonas aeruginosa infection are involved in MMP-12 and MMP-13 upregulation in human carcinoma epithelial cells and a pneumonia mouse model.The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation.HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysThe pharmacological NF-κB inhibitor BAY11-7082 induces cell apoptosis and inhibits the migration of human uveal melanoma cellsProtein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infectionNF-kappa B as a target for cancer therapy.
P2860
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P2860
Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@en
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@nl
type
label
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@en
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@nl
prefLabel
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@en
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@nl
P2093
P921
P1433
P1476
Bay 11-7082 inhibits transcrip ...... y adult T-cell leukemia cells.
@en
P2093
Kunihiro Tsukasaki
Masahiro Fujii
Masao Tomonaga
Naoki Mori
Shuichi Ikeda
Yasuaki Yamada
Yoshihiro Yamasaki
P304
P356
10.1182/BLOOD-2002-01-0151
P407
P577
2002-09-01T00:00:00Z