Size, motion, and function of the SecY translocon revealed by molecular dynamics simulations with virtual probes.
about
Regulation of the Protein-Conducting Channel by a Bound RibosomeMolecular insight into the steric shielding effect of PEG on the conjugated staphylokinase: biochemical characterization and molecular dynamics simulationHydrophobically stabilized open state for the lateral gate of the Sec translocon.Probing the SecYEG translocation pore size with preproteins conjugated with sizable rigid spherical molecules.Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA.Marginally hydrophobic transmembrane α-helices shaping membrane protein folding.Direct simulation of early-stage Sec-facilitated protein translocationLong-timescale dynamics and regulation of Sec-facilitated protein translocation.Molecular simulations of protein dynamics: new windows on mechanisms in biology.The structure of the Sec complex and the problem of protein translocation.Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon.All roads lead to Rome (but some may be harder to travel): SRP-independent translocation into the endoplasmic reticulum.Sec-mediated transport of posttranslationally dehydrated peptides in Lactococcus lactis.The SecY complex forms a channel capable of ionic discrimination.Synthetic peptides identify a second periplasmic site for the plug of the SecYEG protein translocation complex.Translocation of a thioether-bridged azurin peptide fragment via the sec pathway in Lactococcus lactis.The SecA protein deeply penetrates into the SecYEG channel during insertion, contacting most channel transmembrane helices and periplasmic regions.The way is the goal: how SecA transports proteins across the cytoplasmic membrane in bacteria.Deregulation of the SecYEG translocation channel upon removal of the plug domain.Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy.
P2860
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P2860
Size, motion, and function of the SecY translocon revealed by molecular dynamics simulations with virtual probes.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
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@zh-sg
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2006年學術文章
@zh-hant
name
Size, motion, and function of ...... mulations with virtual probes.
@en
Size, motion, and function of ...... mulations with virtual probes.
@nl
type
label
Size, motion, and function of ...... mulations with virtual probes.
@en
Size, motion, and function of ...... mulations with virtual probes.
@nl
prefLabel
Size, motion, and function of ...... mulations with virtual probes.
@en
Size, motion, and function of ...... mulations with virtual probes.
@nl
P2860
P1433
P1476
Size, motion, and function of ...... mulations with virtual probes.
@en
P2093
Ioan Andricioaei
P2860
P304
P356
10.1529/BIOPHYSJ.105.073304
P407
P577
2006-02-03T00:00:00Z