about
Preparation of photo-cross-linked small molecule affinity matrices for affinity selection of protein targets for biologically active small molecules.Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D.Photo-cross-linked small-molecule affinity matrix as a tool for target identification of bioactive small molecules.Vicenistatin induces early endosome-derived vacuole formation in mammalian cells.Synthesis and structure-activity relationship study of FD-891: importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells.Total Synthesis and Biological Evaluation of Irciniastatin A (a.k.a. Psymberin) and Irciniastatin B.Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1.KSRP/FUBP2 Is a Binding Protein of GO-Y086, a Cytotoxic Curcumin Analogue.Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning.Synthesis and structure-activity relationship of vicenistatin, a cytotoxic 20-membered macrolactam glycoside.Structure-activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof.Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells.The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin.Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway.Total synthesis and determination of the absolute configuration of (-)-idesolide.Syntheses of naturally occurring cytotoxic [7.7]paracyclophanes, (-)-cylindrocyclophane A and its enantiomer, and implications for biological activity.Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions.Structure-affinity relationship study of bleomycins and Shble protein by use of a chemical array.Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis.Design and synthesis of the penta(acetoxymethyl) ester of dioctanoyl phosphatidylinositol-3,5-bisphosphate.A concise and unified strategy for synthesis of the C1-C18 macrolactone fragments of FD-891, FD-892 and their analogues: formal total synthesis of FD-891.Photo-cross-linked small-molecule affinity matrix for facilitating forward and reverse chemical genetics.A mild two-step propargylation of aromatic bioactive small molecules.Studies aimed at the total synthesis of azadirachtin. A modeled connection of C-8 and C-14 in azadirachtin.Synthesis and biological activities of reveromycin A and spirofungin A derivatives.Photo-cross-linked small-molecule microarrays as chemical genomic tools for dissecting protein-ligand interactions.SPR imaging of photo-cross-linked small-molecule arrays on gold.Concise, Protecting-Group-Free Synthesis of (+)-Nemonapride via Eu(OTf)3-Catalyzed Aminolysis of 3,4-Epoxy Alcohol.Asymmetric Total Synthesis of Heronamides A-C: Stereochemical Confirmation and Impact of Long-Range Stereochemical Communication on the Biological ActivityTotal synthesis of methyl sarcophytoateCleavable linker for photo-cross-linked small-molecule affinity matrixTotal synthesis of methyl sarcophytoate, a marine natural biscembranoidSyntheses and biological evaluation of irciniastatin A and the C1-C2 alkyne analogueDetection of cytochrome P450 substrates by using a small-molecule droplet array on an NADH-immobilized solid surfaceSynthetic studies on daphnicyclidin A: enantiocontrolled construction of the BCD ring systemConcise entry to both enantiomers of 8-oxabicyclo[3.2.1]oct-3-en-2-one based on novel oxidative etherification: formal synthesis of (+)-sundiversifolideAn expedient route to a potent gastrin/CCK-B receptor antagonist (+)-AG-041RHighly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellinesStructure-Activity Relationships of the Antitumor C5-Curcuminoid GO-Y030
P50
Q34037271-56306F8A-25A7-4AD4-B987-F8BE887E45E0Q34210438-B4F9E118-4E20-4402-A19D-14A7A122077AQ38748330-71AADE05-4B16-4912-AA0D-D021209FE195Q38776251-8AE2723D-C6A6-4A87-BFAF-DDF9A691B3ACQ38799205-B4B45F4A-3096-4A4D-A841-9D37494A244DQ38821589-DCB0CE4F-0F35-4A3F-B7C3-E55AAD18E898Q38915883-8A8233E9-B0CB-46EB-AB07-C7ED9F380973Q39156057-190C0B40-538D-452C-96C0-554A01144A35Q39220312-D2EF89F9-E43D-41BC-9BDA-85B169F90A3EQ39270757-78D7CBE9-E702-4E38-BE54-467999324B76Q39754316-B2C60A57-0C86-4B8C-93F8-10CCCD8E421AQ40428553-5974637E-670A-40FE-AC75-578FF5E9B2A5Q40541748-956D1AAF-6FF6-4C79-9BC5-7733D09955C0Q42116824-B3E9BB65-0B1A-4C37-9685-6D2E2EB543DDQ42870361-7EF79F00-E7B5-4C2A-881A-7CA1EEC140E3Q43171803-5BC7EE90-45F3-4C57-9349-09601250BD0DQ43286027-17C33A86-0A8B-4583-8877-B17A1F0BB79CQ44669676-BF928748-5C4F-4DAB-B260-24CF9F25A0E7Q46119919-CE826B93-2E21-4058-BA80-B9129C763616Q47860228-DEFB79B8-3E5C-4C1A-84F9-FFF24B16C17FQ48887033-C09FBDF2-4760-4022-BD40-1724E5C390B1Q51051212-674406D5-6BF2-4917-AF1E-9CDC643E95BAQ51474151-B3FD4BC7-F603-482C-9F4F-73E619FF7A43Q52542833-421D4DF9-4662-4629-95D0-C02EE9592C47Q52598428-24F7D129-B2BA-4BE3-87DE-9388F44A2213Q53473789-948F5962-EC0A-413C-9619-57CBD82B7E47Q53487147-53FC4CEA-935B-46F6-A4EA-2C4B2D3A1E8AQ53544440-5DB05647-73E7-44DA-8F12-B2776A9F5F54Q53748182-03F94360-F804-42C9-AD4F-572A6435D2B4Q57182505-2663F648-66A6-4B24-9D5D-E24A2522940EQ80689487-D1223E61-BA49-43B3-B147-A23E67CDEDAFQ82312978-C29CF18B-F375-441A-880E-CA7065DC2496Q82823499-481747BC-19AC-4EEC-AFF4-F0125764AD05Q82826538-6364783D-B171-4CA0-8E1F-6A6F3C6C32BCQ82916315-DC037CB8-D590-48E2-87CE-12CC7273D1EBQ83555444-62C62880-6D1F-4B2A-AC58-2AFA2E46EE04Q84314668-9E4C8B0B-DDFA-4351-9088-0AE2AEAB19F8Q84495234-3CFA1806-BF0C-45AE-849F-410D6B908061Q84717069-57B409EE-FC81-4E26-A26C-8205ADDE5610Q85965691-8E8561E9-6B3A-4501-9A63-675A0F6F745C
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Naoki Kanoh
@ast
Naoki Kanoh
@en
Naoki Kanoh
@es
Naoki Kanoh
@nl
Naoki Kanoh
@sl
type
label
Naoki Kanoh
@ast
Naoki Kanoh
@en
Naoki Kanoh
@es
Naoki Kanoh
@nl
Naoki Kanoh
@sl
prefLabel
Naoki Kanoh
@ast
Naoki Kanoh
@en
Naoki Kanoh
@es
Naoki Kanoh
@nl
Naoki Kanoh
@sl
P108
P1053
F-5765-2010
P106
P1153
7004358877
P21
P31
P3829
P496
0000-0002-4382-3715