The first generation of β-galactosidase-responsive prodrugs designed for the selective treatment of solid tumors in prodrug monotherapy.
about
Programmed activation of cancer cell apoptosis: A tumor-targeted phototherapeutic topoisomerase I inhibitorα-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studiesMarine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Optical imaging of targeted β-galactosidase in brain tumors to detect EGFR levelsIntracellular GSH-activated galactoside photosensitizers for targeted photodynamic therapy and chemotherapy.Dual-targeting pro-apoptotic peptide for programmed cancer cell death via specific mitochondria damageSelf-immolative spacers: kinetic aspects, structure-property relationships, and applications.Rational design of multifunctional small-molecule prodrugs for simultaneous suppression of cancer cell growth and metastasis in vitro and in vivo.Bioinspired Nano-Prodrug with Enhanced Tumor Targeting and Increased Therapeutic Efficiency.Biotin-guided anticancer drug delivery with acidity-triggered drug release."Double gating"--a concept for enzyme-responsive imaging probes aiming at high tissue specificity.Targeting the tumour microenvironment with an enzyme-responsive drug delivery system for the efficient therapy of breast and pancreatic cancers.Cytosolic delivery of large proteins using nanoparticle-stabilized nanocapsules.Enzyme-mediated nutrient release: glucose-precursor activation by β-galactosidase to induce bacterial growth.An enzyme-responsive system programmed for the double release of bioactive molecules through an intracellular chemical amplification process.New insight on the structural features of the cytotoxic auristatins MMAE and MMAF revealed by combined NMR spectroscopy and quantum chemical modelling.Three-Arm, Biotin-Tagged Carbazole-Dicyanovinyl-Chlorambucil Conjugate: Simultaneous Tumor Targeting, Sensing, and Photoresponsive Anticancer Drug Delivery.A dendritic β-galactosidase-responsive folate-monomethylauristatin E conjugate.From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release.Redox-responsive degradable honeycomb manganese oxide nanostructures as effective nanocarriers for intracellular glutathione-triggered drug release.
P2860
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P2860
The first generation of β-galactosidase-responsive prodrugs designed for the selective treatment of solid tumors in prodrug monotherapy.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
The first generation of β-gala ...... tumors in prodrug monotherapy.
@en
The first generation of β-gala ...... tumors in prodrug monotherapy.
@nl
type
label
The first generation of β-gala ...... tumors in prodrug monotherapy.
@en
The first generation of β-gala ...... tumors in prodrug monotherapy.
@nl
prefLabel
The first generation of β-gala ...... tumors in prodrug monotherapy.
@en
The first generation of β-gala ...... tumors in prodrug monotherapy.
@nl
P2093
P2860
P356
P1476
The first generation of β-gala ...... tumors in prodrug monotherapy
@en
P2093
Alain Le Pape
Brigitte Renoux
Isabelle Tranoy-Opalinski
Jonathan Clarhaut
Mikaël Thomas
Stéphanie Lerondel
Sébastien Papot
Thibaut Legigan
P2860
P304
11606-11610
P356
10.1002/ANIE.201204935
P407
P577
2012-09-20T00:00:00Z