Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. - Wikidata - wikimedia - TriplyDB

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

http://www.wikidata.org/entity/Q39292236

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Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis.Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents Plant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathway Non-specific protein modifications by a phytochemical induce heat shock response for self-defense Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer.Bioactive sesquiterpenes from Curcuma ochrorhiza and Curcuma heyneana.Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials.Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells Dietary zerumbone prevents against ultraviolet B-induced cataractogenesis in the mouse.Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA accumulation.Possible Contribution of Zerumbone-Induced Proteo-Stress to Its Anti-Inflammatory Functions via the Activation of Heat Shock Factor 1.Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells.Cancer and diet: How are they related?Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells.Dual roles of Nrf2 in cancer.Electrophiles in foods: the current status of isothiocyanates and their chemical biology.Solar radiation induced skin damage: review of protective and preventive options.Plant volatiles: production, function and pharmacology.Hormetics: dietary triggers of an adaptive stress response.Update on the chemopreventive effects of ginger and its phytochemicals.Target molecules of food phytochemicals: food science bound for the next dimension.Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases.Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions.6-Gingerol Mediates its Anti Tumor Activities in Human Oral and Cervical Cancer Cell Lines through Apoptosis and Cell Cycle Arrest.Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals.Larvicidal and repellent potential of Zingiber nimmonii (J. Graham) Dalzell (Zingiberaceae) essential oil: an eco-friendly tool against malaria, dengue, and lymphatic filariasis mosquito vectors?The role of Nrf2-Keap1 axis in colorectal cancer, progression, and chemoresistance.Exploring the immunomodulatory and anticancer properties of zerumbone.1,2,3,4,6-penta-O-galloyl-beta-D-glucose up-regulates heme oxygenase-1 expression by stimulating Nrf2 nuclear translocation in an extracellular signal-regulated kinase-dependent manner in HepG2 cells.Enhancing the anti-inflammatory activity of chalcones by tuning the Michael acceptor site.Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats.The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-induced hepatic injury.Hepatoprotective, antioxidant, and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats.Cytotoxic and cytoprotective effects of tryptamine-4,5-dione on neuronal cells: a double-edged sword.Allantopyrone A activates Keap1-Nrf2 pathway and protects PC12 cells from oxidative stress-induced cell death.A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extraction from Ginger Rhizomes.Non-specific protein modifications may be novel mechanism underlying bioactive phytochemicals.

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P2860

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

http://www.wikidata.org/entity/Q39292236

description

2004 nî lūn-bûn

@nan

2004年の論文

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2004年論文

@yue

2004年論文

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2004年論文

@zh-hk

2004年論文

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2004年論文

@zh-tw

2004年论文

@wuu

2004年论文

@zh

2004年论文

@zh-cn

name

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@en

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@nl

type

label

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@en

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@nl

prefLabel

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@en

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@nl

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P356

J.FEBSLET.2004.07.042

P1433

P1476

Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.

@en

P2093

Akira Murakami

http://www.w3.org/2001/XMLSchema#string

Chiho Yoshida

http://www.w3.org/2001/XMLSchema#string

Hajime Ohigashi

http://www.w3.org/2001/XMLSchema#string

Koji Uchida

http://www.w3.org/2001/XMLSchema#string

Toshihiko Osawa

http://www.w3.org/2001/XMLSchema#string

Yoshimasa Nakamura

http://www.w3.org/2001/XMLSchema#string

P2860

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

The ubiquitin system

4-hydroxy-2-nonenal, the end product of lipid peroxidation, is a specific inducer of cyclooxygenase-2 gene expression

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis.

Regulatory mechanisms of cellular response to oxidative stress.

Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite.

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10.1016/J.FEBSLET.2004.07.042

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8407497

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15304356

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