Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.
about
O-glycosylation of glycine-serine linkers in recombinant Fc-fusion proteins: attachment of glycosaminoglycans and other intermediates with phosphorylation at the xylose sugar subunit.Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.A Dual Target-directed Agent against Interleukin-6 Receptor and Tumor Necrosis Factor α ameliorates experimental arthritis.Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammationBiologics in dermatology.Monoclonal antibody treatments for rheumatoid arthritis.Trojan horses and guided missiles: targeted therapies in the war on arthritis.Angiopoietin-2: a multifaceted cytokine that functions in both angiogenesis and inflammation.Small molecules and antibodies for the treatment of psoriasis: a patent review (2010-2015).An affibody-adalimumab hybrid blocks combined IL-6 and TNF-triggered serum amyloid A secretion in vivo.Affibody molecules as engineered protein drugs.Therapeutic targeting of the angiopoietin-TIE pathway.Targeting non-canonical nuclear factor-κB signalling attenuates neovascularization in a novel 3D model of rheumatoid arthritis synovial angiogenesis.Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration.The making of bispecific antibodies2nd PEGS Annual Symposium on Antibodies for Cancer Therapy: April 30-May 1, 2012, Boston, USA.A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A.Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis.A New Venue of TNF Targeting.
P2860
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P2860
Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.
description
2012 nî lūn-bûn
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2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@en
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@nl
type
label
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@en
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@nl
prefLabel
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@en
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@nl
P2093
P2860
P356
P1476
Simultaneous targeting of TNF ...... an in vivo model of arthritis.
@en
P2093
Bridget A Puffer
Carlos F Barbas
David M Hilbert
David W LaFleur
Dimki Patel
Ernest Boyd
Geping Wang
Palanisamy Kanakaraj
Peter A Kiener
Rodger G Smith
P2860
P304
P356
10.4161/MABS.21227
P577
2012-08-06T00:00:00Z