The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling
about
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 productionL-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexinsCharacterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface.Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.Endoplasmic reticulum stress: its role in disease and novel prospects for therapy.Targeting GRP78 and antiestrogen resistance in breast cancer.Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells.Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro.
P2860
Q28534981-9053177B-6EC8-4CDF-BFC6-E56FEDE7D15BQ34755622-699EDBBD-3A19-483F-AF6E-6D49ACF2373CQ35221505-ED320280-8F94-4CF1-BA9A-11189272DB91Q36120369-2400F0DC-D37B-494A-83EB-2F359D0AACDDQ37288073-B8FDC6CE-3DDD-4769-9E43-EA7149A469D8Q38111800-1A57F77A-685A-42F3-B16D-CBB59317D4E4Q38739821-2384F2E6-01AA-4FE4-936C-174AE789C311Q38972005-2816B09B-5809-40E1-AD08-9BDD27319679
P2860
The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling
description
2012 nî lūn-bûn
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name
The Escherichia coli subtilase ...... H-terminal-dependent signaling
@en
The Escherichia coli subtilase ...... -terminal-dependent signaling.
@nl
type
label
The Escherichia coli subtilase ...... H-terminal-dependent signaling
@en
The Escherichia coli subtilase ...... -terminal-dependent signaling.
@nl
prefLabel
The Escherichia coli subtilase ...... H-terminal-dependent signaling
@en
The Escherichia coli subtilase ...... -terminal-dependent signaling.
@nl
P2093
P2860
P356
P1476
The Escherichia coli subtilase ...... H-terminal-dependent signaling
@en
P2093
Gustaaf G de Ridder
James C Paton
Jerry P Eu
Salvatore V Pizzo
P2860
P304
32755-32769
P356
10.1074/JBC.M112.399808
P407
P577
2012-07-31T00:00:00Z